Evidence map›Paper›PMID 23323856›Full record

ArticleBMC bioinformatics2013

XperimentR: painless annotation of a biological experiment for the laboratory scientist.

Chris D Tomlinson, Geraint R Barton, Mark Woodbridge, Sarah A Butcher

Abstract read
In one paragraph

Article in BMC bioinformatics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chris D TomlinsonCentre for Integrated Systems Biology and Bioinformatics, Imperial College London, Sir Ernst Chain Building, South Kensington Campus, London SW7 2AZ, UK. chris.tomlinson@imperial.ac.uk
Geraint R Barton
Mark Woodbridge
Sarah A Butcher

Funding

Biotechnology and Biological Sciences Research Council BB/C519670/1Biotechnology and Biological Sciences Research Council BB/G003912/1
6 · The paper itself

Abstract

backgroundToday's biological experiments often involve the collaboration of multidisciplinary researchers utilising several high throughput 'omics platforms. There is a requirement for the details of the experiment to be adequately described using standardised ontologies to enable data preservation, the analysis of the data and to facilitate the export of the data to public repositories. However there are a bewildering number of ontologies, controlled vocabularies, and minimum standards available for use to describe experiments. There is a need for user-friendly software tools to aid laboratory scientists in capturing the experimental information.

resultsA web application called XperimentR has been developed for use by laboratory scientists, consisting of a browser-based interface and server-side components which provide an intuitive platform for capturing and sharing experimental metadata. Information recorded includes details about the biological samples, procedures, protocols, and experimental technologies, all of which can be easily annotated using the appropriate ontologies. Files and raw data can be imported and associated with the biological samples via the interface, from either users' computers, or commonly used open-source data repositories. Experiments can be shared with other users, and experiments can be exported in the standard ISA-Tab format for deposition in public databases. XperimentR is freely available and can be installed natively or by using a provided pre-configured Virtual Machine. A guest system is also available for trial purposes.

conclusionWe present a web based software application to aid the laboratory scientist to capture, describe and share details about their experiments.

Indexed as

Research DesignSoftwareInformation SystemsInternetLaboratory PersonnelResearchResearch PersonnelUser-Computer InterfaceVocabulary, Controlled

Identifiers

PMID23323856
PMCPMC3571946

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.