Trial reportSexually transmitted diseases2013
Randomized controlled trial on the effectiveness of counseling messages for avoiding unprotected sexual intercourse during sexually transmitted infection and reproductive tract infection treatment among female sexually transmitted infection clinic patients.
Trial report in Sexually transmitted diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021Guideline
- Sexually transmitted diseases treatment guidelines, 2015.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2015Guideline
- Effectiveness of erectogenic condom against semen exposure among women in Vietnam: Randomized controlled trial.PloS one · 2022Trial
- Effects of initiating a contraceptive implant on subsequent condom use: A randomized controlled trial.Contraception · 2015Trial
- Intravaginal cleansing among women attending a sexually transmitted infection clinic in Kingston, Jamaica.The West Indian medical journal · 2013Trial
- Application of ADAPT-ITT: adapting an evidence-based HIV/STI mother-daughter prevention intervention for Black male caregivers and girls.BMC public health · 2023Article
- Risky Sexual Behavior and Associated Factors among Adolescents Aged 15-19 Years at Governmental High Schools in Aksum Town, Tigray, Ethiopia, 2019: An Institution-Based, Cross-Sectional Study.BioMed research international · 2020Article
- PrEP Use Among Female Sex Workers: No Evidence for Risk Compensation.Journal of acquired immune deficiency syndromes (1999) · 2019Observational
- Observational
- Test-Retest Reliability of Self-Reported Sexual Behavior History in Urbanized Nigerian Women.Frontiers in public health · 2017Article
- Substance use and STI acquisition: Secondary analysis from the AWARE study.Drug and alcohol dependence · 2016Observational
- Sexual abstinence and other behaviours immediately following a new STI diagnosis among STI clinic patients: Findings from the Safe in the City trial.Sexually transmitted infections · 2016Article
- An application of propensity score weighting to quantify the causal effect of rectal sexually transmitted infections on incident HIV among men who have sex with men.BMC medical research methodology · 2015Article
- Differences in misreporting of sexual behavior over time: implications for HIV trials.Sexually transmitted diseases · 2015Article
- The use of biomarkers of semen exposure in sexual and reproductive health studies.Journal of women's health (2002) · 2014Article
- Prostate-specific antigen is unlikely to be a suitable biomarker of semen exposure from recent unprotected receptive anal intercourse in men who have sex with men.Sexually transmitted diseases · 2014Article
- Review of HIV in the Caribbean: significant progress and outstanding challenges.Current HIV/AIDS reports · 2014Review
- Biological markers of sexual activity: tools for improving measurement in HIV/sexually transmitted infection prevention research.Sexually transmitted diseases · 2013Review
- Optimal methods for collecting and storing vaginal specimens for prostate-specific antigen testing in research studies.Contraception · 2013Article
- Exploring discordance between biologic and self-reported measures of semen exposure: a qualitative study among female patients attending an STI clinic in Jamaica.AIDS and behavior · 2013Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundThe effectiveness of counseling messages to avoid unprotected sex during short-term treatment for curable sexually transmitted infections is unknown.
methodsWe randomized 300 female STI clinic patients 18 years or older with cervicitis and/or vaginal discharge in Kingston, Jamaica, in 2010 to 2011, to 1 of 2 counseling messages for their course of syndromic treatment: abstinence only or abstinence backed up by condom use. At a follow-up visit 6 days afterward, we collected vaginal swabs to test for prostate-specific antigen (PSA), a biological marker of recent semen exposure, and administered a questionnaire assessing sexual behavior.
resultsNo differences were found in the proportions of women testing positive for PSA at follow-up in the abstinence-plus-condom group (11.9%) and abstinence-only group (8.4%) (risk difference, 3.5; 95% confidence interval, -3.5 to 10.5). There also was no significant difference in reporting of unprotected sex between groups. Reporting a history of condom use before enrollment significantly modified the effect of counseling arm on PSA positivity (P = 0.03). Among those reporting recent condom use, 10.3% in the abstinence-only arm and 4.8% in the abstinence-plus-condom arm tested positive for PSA. Conversely, among those not reporting recent condom use, 6.5% in the abstinence-only arm and 17.3% in the abstinence-plus-condom arm had PSA detected.
conclusionsWe found no evidence to support the superiority of either counseling message. Post hoc analyses suggest that women with recent condom experience may benefit significantly more from abstinence-plus-condom messages, whereas women without such experience may benefit significantly more from abstinence-only messages. Providers should weigh individual condom use history when determining the most appropriate counseling message.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.