SynthesisEnvironmental health : a global access science source2013
Environmental risk factors of pregnancy outcomes: a summary of recent meta-analyses of epidemiological studies.
Synthesis in Environmental health : a global access science source, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
101 citing papers in PubMed, 11 syntheses or guidelines pooled it, 225 citations in OpenAlex.
- Association between prenatal environmental tobacco smoke exposure and preterm birth: A systematic review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2025Pooled it
- Exposure to drinking water pollutants and non-syndromic birth defects: a systematic review and meta-analysis synthesis.BMJ open · 2024Pooled it
- Environmental exposures and adverse pregnancy outcomes in Ethiopia: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Household polluting cooking fuels and adverse birth outcomes: An updated systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- The associations of air pollution exposure during pregnancy with fetal growth and anthropometric measurements at birth: a systematic review and meta-analysis.Environmental science and pollution research international · 2019Pooled it
- Maternal fine particulate matter (PMEnvironmental science and pollution research international · 2019Pooled it
- Different exposure levels of fine particulate matter and preterm birth: a meta-analysis based on cohort studies.Environmental science and pollution research international · 2017Pooled it
- The association between fine particulate matter exposure during pregnancy and preterm birth: a meta-analysis.BMC pregnancy and childbirth · 2015Pooled it
- Use of Systematic Review and Meta-Analysis in Environmental Health Epidemiology: a Systematic Review and Comparison with Guidelines.Current environmental health reports · 2015Pooled it
- Passive smoking in the etiology of non-syndromic orofacial clefts: a systematic review and meta-analysis.PloS one · 2015Pooled it
- Ambient air pollution and adverse birth outcomes: a systematic review and meta-analysis.Journal of Zhejiang University. Science. BPooled it
- Effect of a chimney-fitted improved stove on pregnancy outcomes in Northwest Ethiopia: a randomized controlled trial.BMC pregnancy and childbirth · 2024Trial
- Environmental Exposure-Induced Epigenetic Modifications and Adverse Pregnancy Outcomes: A Systematic Review.Cureus · 2026Review
- Depression, anxiety, and stress across the perinatal period: longitudinal trends and associations with adverse outcomes : Article Type: Original Paper.BMC pregnancy and childbirth · 2026Article
- Traffic-Related Air Pollution and Birth Weight: The Roles of Noise, Placental Function, Green Space, Physical Activity, and Socioeconomic Status (FRONTIER).Research report (Health Effects Institute) · 2026Article
- How to Better Assess the Real Role of the Environment in Pregnancy, From Past to Future: A Relational Open Data Infrastructure Covering 30,000 Births.Health science reports · 2026Article
- Exposure to air and water pollution during pregnancy and risk of adverse perinatal outcomes in São Paulo State: protocol for a retrospective population-based cohort study.BMJ public health · 2026Article
- Wastewater-based surveillance for community exposome surveillance, Louisville, Kentucky.Discover water · 2026Article
- Review
- Global, regional, and national epidemiology of congenital birth defects in children from 1990 to 2021: a cross-sectional study.BMC pregnancy and childbirth · 2025Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVarious epidemiological studies have suggested associations between environmental exposures and pregnancy outcomes. Some studies have tempted to combine information from various epidemiological studies using meta-analysis. We aimed to describe the methodologies used in these recent meta-analyses of environmental exposures and pregnancy outcomes. Furthermore, we aimed to report their main findings.
methodsWe conducted a bibliographic search with relevant search terms. We obtained and evaluated 16 recent meta-analyses.
resultsThe number of studies included in each reported meta-analysis varied greatly, with the largest number of studies available for environmental tobacco smoke. Only a small number of the studies reported having followed meta-analysis guidelines or having used a quality rating system. Generally they tested for heterogeneity and publication bias. Publication bias did not occur frequently.The meta-analyses found statistically significant negative associations between environmental tobacco smoke and stillbirth, birth weight and any congenital anomalies; PM2.5 and preterm birth; outdoor air pollution and some congenital anomalies; indoor air pollution from solid fuel use and stillbirth and birth weight; polychlorinated biphenyls (PCB) exposure and birth weight; disinfection by-products in water and stillbirth, small for gestational age and some congenital anomalies; occupational exposure to pesticides and solvents and some congenital anomalies; and agent orange and some congenital anomalies.
conclusionsThe number of meta-analyses of environmental exposures and pregnancy outcomes is small and they vary in methodology. They reported statistically significant associations between environmental exposures such as environmental tobacco smoke, air pollution and chemicals and pregnancy outcomes.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.