Evidence map›Paper›PMID 23320888›Full record

ArticleLeukemia & lymphoma2013

A preliminary study of a health related quality of life assessment of priority symptoms in advanced lymphoma: the National Comprehensive Cancer Network-Functional Assessment of Cancer Therapy - Lymphoma Symptom Index.

Fay J Hlubocky, Kimberly Webster, Jennifer Beaumont, John Cashy, Diane Paul, Amy Abernethy, Karen L Syrjala, Jamie Von Roenn, David Cella

2 registry-linked trialsAbstract read
In one paragraph

Article in Leukemia & lymphoma, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05064787 nacompletednot on this mapstarted 2022, after this paper: background citation

Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy

TypeinterventionalSponsorPack HealthRan2022 to 2024Enrolled45ConditionsLymphoma, Lymphoma, B-Cell, Leukemia, Multiple MyelomaArmsDigital Health Coaching
NCT05199961 naterminatednot on this mapstarted 2022, after this paper: background citation

Quality of Life of Adults With Diffuse Large B-cell Lymphoma Treated With Tisagenlecleucel

TypeinterventionalSponsorPack HealthRan2022 to 2022Enrolled4ConditionsLymphoma, Large B-Cell, DiffuseArmsDigital Health Coaching
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
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  5. Trial
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Quality of Life and Survivorship in Lymphoma.Current oncology reports · 2022
    Review
  14. Article
  15. Validity of a single-item indicator of treatment side effect bother in a diverse sample of cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fay J HlubockyDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Northwestern Medical Faculty Foundation, Evanston, IL, USA. fhlubock@medicine.bsd.uchicago.edu
Kimberly Webster
Jennifer Beaumont
John Cashy
Diane Paul
Amy Abernethy
Karen L Syrjala
Jamie Von Roenn
David Cella

Funding

Internet Studies to Enhance Long Term Survivorship after Hematologic MalignancyR01CA160684 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI SYRJALA, KAREN LESLIE · 2011 to 2015
$3.4M
Interdisciplinary Studies to Enhance Long Term SurvivalR01CA112631 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI SYRJALA, KAREN LESLIE · 2005 to 2010
$2.8M
NCI NIH HHS R01 CA112631NCI NIH HHS R01 CA160684
6 · The paper itself

Abstract

Despite the recent advances in cancer therapeutics for lymphoma (Lym), a continuum of disease, treatment and psychological challenges, adversely impacting health-related quality of life, remain for the clinical management of the patient with Lym. In response, this study presents the development and validation of the National Comprehensive Cancer Network-Functional Assessment of Cancer Therapy (NCCN-FACT) Lymphoma Symptom Index-18 (FLymSI-18). Patients with advanced Lym (n = 50) rated the significance of 40 symptoms, and hematologist-oncologists (n = 10) rated these symptoms according to importance and disease-related or treatment-related origin. Patient symptom priorities were unified with clinician priorities for symptom measurement in Lym for instrument development. Reliability estimates indicate that FLymSI-18 has acceptable internal consistency (α = 0.87), content validity and concurrent validity as indicated by moderate to strong correlations with the FACIT (Functional Assessment of Chronic Illness Therapy). Overall, the FLymSI-18 provides evidence for its reliability and validity as a brief assessment of the most important symptoms associated with advanced Lym in the clinical trial research environment.

Indexed as

Quality of LifeAdultAgedCross-Sectional StudiesFemaleHealth Care SurveysHumansLymphomaMaleMiddle AgedNeoplasm StagingOutcome Assessment, Health CareReproducibility of ResultsSelf ReportSocioeconomic Factors

Identifiers

PMID23320888
PMCPMC5889924

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.