ArticleCritical care research and practice2012
Impact of changes in perinatal care on neonatal respiratory outcome and survival of preterm newborns: an overview of 15 years.
Article in Critical care research and practice, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Sedation of newborn infants for the INSURE procedure, are we sure?BioMed research international · 2013Pooled it
- Global, regional and national disease burden of neonatal disorders from 2000 to 2021 and the comparison before and during COVID-19: a systematic analysis.BMC public health · 2025Article
- Ventilation-Induced Lung Injury (VILI) in Neonates: Evidence-Based Concepts and Lung-Protective Strategies.Journal of clinical medicine · 2022Review
- Inhaled Pharmacotherapy for Neonates: A Narrative Review.Turkish archives of pediatrics · 2022Article
- Outcomes of multiple gestation births compared to singleton: analysis of multicenter KID database.Maternal health, neonatology and perinatology · 2021Article
- Article
- Respiratory Care for the Ventilated Neonate.Canadian respiratory journal · 2018Review
- Cytokine profiles at birth and the risk of developing severe respiratory distress and chronic lung disease.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Article
- Drug utilisation profile in the neonatal unit of a university hospital: a prospective observational study in Brazil.International journal of clinical pharmacy · 2015Observational
- Alterations in cortical thickness development in preterm-born individuals: Implications for high-order cognitive functions.NeuroImage · 2015Article
- Oxygen, gastrin-releasing Peptide, and pediatric lung disease: life in the balance.Frontiers in pediatrics · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Survival and outcomes for preterm infants with respiratory distress syndrome (RDS) have improved over the past 30 years. We conducted a study to assess the changes in perinatal care and delivery room management and their impact on respiratory outcome of very low birth weight newborns, over the last 15 years. A comparison between two epochs was performed, the periods before and after 2005, when early nasal continuous positive airway pressure (NCPAP) and Intubation-SURfactant-Extubation (INSURE) were introduced in our center. Three hundred ninety-five clinical records were assessed, 198 (50.1%) females, gestational age 29.1 weeks (22-36), and birth weight 1130 g (360-1498). RDS was diagnosed in 247 (62.5%) newborns and exogenous surfactant was administered to 217 (54.9%). Thirty-three (8.4%) developed bronchopulmonary dysplasia (BPD), and 92 (23%) were deceased. With the introduction of early NCPAP and INSURE, there was a decrease on the endotracheal intubation need and invasive ventilation (P < 0.0001), oxygen therapy (P = 0.002), and mortality (P < 0.0001). The multivariate model revealed a nonsignificant reduction in BPD between the two epochs (OR = 0.86; 95% CI 0.074-9.95; P = 0.9). The changes in perinatal care over the last 15 years were associated to an improvement of respiratory outcome and survival, despite a nonsignificant decrease in BPD rate.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.