ArticleEvidence-based complementary and alternative medicine : eCAM2012
Banxia baizhu tianma decoction for essential hypertension: a systematic review of randomized controlled trials.
Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Banxia baizhu tianma decoction, a Chinese herbal formula, for hypertension: Integrating meta-analysis and network pharmacology.Frontiers in pharmacology · 2022Pooled it
- Meta-analysis of the effectiveness of traditional Chinese herbal formula Zhen Wu Decoction for the treatment of hypertension.BMJ open · 2015Pooled it
- Trial
- Observational
- The role of Chinese herbal medicine in the regulation of oxidative stress in treating hypertension: from therapeutics to mechanisms.Chinese medicine · 2024Review
- Food processing drives the toxic lectin reduction and bioactive peptide enhancement inCurrent research in food science · 2024Article
- Network Pharmacology and Molecular Docking Combined to Analyze the Molecular and Pharmacological Mechanism ofCurrent issues in molecular biology · 2021Article
- Toward the Development of Personalized Syndrome Discriminant Systems: A Discriminant System for Hypertension with LiverEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Traditional Chinese Medicine for Essential Hypertension: A Clinical Evidence Map.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Emerging Applications of Metabolomics in Traditional Chinese Medicine Treating Hypertension: Biomarkers, Pathways and More.Frontiers in pharmacology · 2019Review
- Therapeutic Efficacy and Safety of Traditional Chinese Medicine Classic Herbal FormulaFrontiers in pharmacology · 2018Article
- Chinese herbal medicine for the treatment of primary hypertension: a methodology overview of systematic reviews.Systematic reviews · 2016Review
- Puerarin and betahistine treatment of vertebrobasilar ischemia vertigo: A meta-analysis of randomized controlled trials.Experimental and therapeutic medicine · 2016Article
- Chinese patent medicine tongxinluo capsule for hypertension: a systematic review of randomised controlled trials.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Traditional chinese medicine syndromes for essential hypertension: a literature analysis of 13,272 patients.Evidence-based complementary and alternative medicine : eCAM · 2014Review
- Treatment of cardiovascular disease by traditional Chinese medicine against pregnane X receptor.BioMed research international · 2014Article
- Chinese herbal formulas for treating hypertension in traditional Chinese medicine: perspective of modern science.Hypertension research : official journal of the Japanese Society of Hypertension · 2013Review
- Chinese herbal medicine qi ju di huang wan for the treatment of essential hypertension: a systematic review of randomized controlled trials.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Evidence-based chinese medicine for hypertension.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Chinese herbal medicine for the treatment of obesity-related hypertension.Evidence-based complementary and alternative medicine : eCAM · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives. To assess the current clinical evidence of Banxia Baizhu Tianma Decoction (BBTD) for essential hypertension (EH). Search Strategy. Electronic databases were searched until July 2012. Inclusion Criteria. We included randomized clinical trials testing BBTD against placebo, antihypertensive drugs, or combined with antihypertensive drugs against antihypertensive drugs. Data Extraction and Analyses. Study selection, data extraction, quality assessment, and data analyses were conducted according to Cochrane standards. Results. 16 randomized trials were included. Methodological quality of the included trials was evaluated as generally low. 2 trials compared prescriptions based on BBTD using alone with antihypertensive drugs. Meta-analysis showed no significant effect of modified BBTD compared with captopril in systolic blood pressure (MD: -0.75 (-5.77, 4.27); P = 0.77) and diastolic blood pressure (MD: -0.75 (-2.89, 1.39); P = 0.49). 14 trials compared the combination of BBTD or modified BBTD plus antihypertensive drugs with antihypertensive drugs. Meta-analysis showed there are significant beneficial effect on systolic blood pressure in the combination group compare to the antihypertensive drugs (MD: -4.33 (-8.44, -0.22); P = 0.04). The safety of BBTD is uncertain. Conclusions. There is encouraging evidence of BBTD for lowering SBP, but evidence remains weak. Rigorously designed trials are warranted to confirm these results.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.