ArticleArchives of medical science : AMS2012
Role of selenium and zinc in the pathogenesis of food allergy in infants and young children.
Article in Archives of medical science : AMS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 41 citations in OpenAlex.
- Zinc Deficiency and Zinc Supplementation in Allergic Diseases.Biomolecules · 2024Review
- Review
- Nutritional risks in children with food allergy.Turkish journal of medical sciences · 2023Article
- Micronutrients and the Risk of Allergic Diseases in School Children.International journal of environmental research and public health · 2022Article
- Effect of Different Cooking Methods on Selenium Content of Fish Commonly Consumed in Thailand.Foods (Basel, Switzerland) · 2022Article
- Selenium Modulates the Allergic Response to Whey Protein in a Mouse Model for Cow's Milk Allergy.Nutrients · 2021Article
- Serum Zinc and Inflammatory Cytokines in Vitiligo.The Journal of clinical and aesthetic dermatology · 2020Article
- Review
- Evaluation of the serum zinc level in patients with vitiligo.Postepy dermatologii i alergologii · 2017Article
- Establishing the prevalence of low vitamin D in non-immunoglobulin-E mediated gastrointestinal food allergic children in a tertiary centre.The World Allergy Organization journal · 2017Article
- A practical approach to vitamin and mineral supplementation in food allergic children.Clinical and translational allergy · 2015Article
- Dietary elimination of children with food protein induced gastrointestinal allergy - micronutrient adequacy with and without a hypoallergenic formula?Clinical and translational allergy · 2014Article
- Causes, symptoms and prevention of food allergy.Postepy dermatologii i alergologii · 2013Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSelenium and zinc are indispensable microelements for normal functioning and development of the human body. They are cofactors of many enzymes of the antioxidative barrier (selenium - glutathione peroxidase; zinc - superoxide dismutase). The aim of the study was to evaluate the importance of selenium and zinc in the pathogenesis of food allergy in small children. MATERIAL AND
methodsThe study was performed in 134 children with food allergy, aged 1 to 36 months. The control group was composed of 36 children at the same age, without clinical symptoms of food intolerance. Each child had estimated serum levels of zinc and selenium. Furthermore, the authors evaluated activity of glutathione peroxidase (GSH-Px) in erythrocyte lysates and serum. Tests were performed twice, before and after 6-month administration of elimination diet.
resultsThe obtained results showed that children with food allergy had significantly lower concentrations of selenium, zinc and examined enzymes in comparison to children from the control group. Concentration of selenium and zinc as well as activity of examined enzymes increased after application of eliminative diet.
conclusionsIn children with allergy decreased concentrations of selenium and zinc, and lower values of glutathione peroxidase and superoxide dismutase which increased after elimination diet were affirmed. These observations suggest their role in pathogenesis of food allergy. Conducted observations indicate the need to monitor trace elements content in the diet in children with food allergy. The results showed that children with food allergy had a weakened antioxidative barrier.
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