ArticleInternational journal of nanomedicine2013
Gadolinium(3+)-doped mesoporous silica nanoparticles as a potential magnetic resonance tracer for monitoring the migration of stem cells in vivo.
Article in International journal of nanomedicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- pH-Responsive Mesoporous Silica Nanoparticles Loaded with Naringin for Targeted Osteoclast Inhibition and Bone Regeneration.International journal of nanomedicine · 2024Article
- Ion Doped Hollow Silica Nanoparticles as Promising Oligonucleotide Delivery Systems to Mesenchymal Stem Cells.International journal of nanomedicine · 2024Article
- Advanced Hydrogel systems for mandibular reconstruction.Bioactive materials · 2023Review
- Tracking Neural Stem Cells in vivo: Achievements and Limitations.Stem cell reviews and reports · 2022Review
- Porous Nanomaterials Targeting Autophagy in Bone Regeneration.Pharmaceutics · 2021Review
- Imaging Gliomas with Nanoparticle-Labeled Stem Cells.Chinese medical journal · 2018Review
- A promising magnetic resonance stem cell tracer based on natural biomaterials in a biological system: manganese(II) chelated to melanin nanoparticles.International journal of nanomedicine · 2018Article
- Advances in Monitoring Cell-Based Therapies with Magnetic Resonance Imaging: Future Perspectives.International journal of molecular sciences · 2017Review
- High sensitivity of gold nanoparticles co-doped with GdScientific reports · 2016Article
- DNA-gadolinium-gold nanoparticles for in vivo T1 MR imaging of transplanted human neural stem cells.Biomaterials · 2016Article
- Cell tracking technologies for acute ischemic brain injury.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2015Review
- Pre- and postmortem imaging of transplanted cells.International journal of nanomedicine · 2015Review
- The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy.The British journal of radiology · 2014Review
- Iron administration before stem cell harvest enables MR imaging tracking after transplantation.Radiology · 2013Article
- Cellular uptake and imaging studies of glycosylated silica nanoprobe (GSN) in human colon adenocarcinoma (HT 29 cell line).International journal of nanomedicine · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the tracking potential of a magnetic resonance imaging (MRI) probe made of gadolinium-doped mesoporous silica MCM-41 (Gd(2)O(3)@MCM-41) nanoparticles for transplanted bone mesenchymal stem cells (MSCs) and neural stem cells (NSCs) in vivo. The nanoparticles, synthesized using a one-step synthetic method, possess hexagonal mesoporous structures with appropriate assembly of nanoscale Gd(2)O(3) clusters. They show little cytotoxicity against proliferation and have a lower effect on the inherent differentiation potential of these labeled stem cells. The tracking of labeled NSCs in murine brains was dynamically determined with a clinical 3T MRI system for at least 14 days. The migration of labeled NSCs identified by MRI corresponded to the results of immunofluorescence imaging. Our study confirms that Gd(2)O(3)@MCM-41 particles can serve as an ideal vector for long-term MRI tracking of MSCs and NSCs in vivo.
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