ArticleInfectious diseases in obstetrics and gynecology2012
A first look at chorioamnionitis management practice variation among US obstetricians.
Article in Infectious diseases in obstetrics and gynecology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Maternal inflammatory markers for chorioamnionitis in preterm prelabour rupture of membranes: a systematic review and meta-analysis of diagnostic test accuracy studies.Systematic reviews · 2020Pooled it
- Time to antibiotic administration in intra-amniotic infections: impact of cefoxitin monotherapy versus traditional antibiotic therapy.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Risk factors and risk-indicating model for early-onset neonatal sepsis after preterm prelabor rupture of membranes: A historical cohort study.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Revisiting restricted reproductive rights in 2025: what do we need to know now?Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Stewardship opportunities in peripartum infections: a review of quality improvement initiatives and future directions.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Article
- Development and validation of a nomogram for individualized prediction of spontaneous extremely preterm birth at < 28 weeks in twin pregnancy: a retrospective cohort study.Archives of gynecology and obstetrics · 2024Article
- Laboratory markers to identify acute histological chorioamnionitis in febrile parturients undergoing epidural analgesia: a retrospective study.BMC pregnancy and childbirth · 2023Article
- The Association of Patent Ductus Arteriosus with Inflammation: A Narrative Review of the Role of Inflammatory Biomarkers and Treatment Strategy in Premature Infants.International journal of molecular sciences · 2022Review
- Review
- Dominant bacteria and influencing factors of early intestinal colonization in very low birth weight infants: A prospective cohort study.Journal of clinical laboratory analysis · 2022Article
- MicroRNAs miR-4535 and miR-1915-5p in amniotic fluid as predictive biomarkers for chorioamnionitis.Future science OA · 2021Article
- Management of clinical chorioamnionitis: an evidence-based approach.American journal of obstetrics and gynecology · 2020Review
- Risk Factors for Postpartum Maternal Infection Following Spontaneous Vaginal Delivery Complicated by Chorioamnionitis.AJP reports · 2020Article
- Early-Onset Sepsis Risk Calculator Integration Into an Electronic Health Record in the Nursery.Pediatrics · 2019Article
- Determinants of Initial Antibiotic Duration in Very Low Birth Weight Neonates.Infectious diseases and therapy · 2019Article
- Incidence of early-onset sepsis in infants born to women with clinical chorioamnionitis.Journal of perinatal medicine · 2018Article
- What's the harm? Risks and benefits of evolving rule-out sepsis practices.Journal of perinatology : official journal of the California Perinatal Association · 2018Review
- Methods to decrease variability in histological scoring in placentas from a cohort of preterm infants.BMJ open · 2017Article
- Antibiotic Therapy for Chorioamnionitis to Reduce the Global Burden of Associated Disease.Frontiers in pharmacology · 2017Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Objective. To examine practice patterns for diagnosis and treatment of chorioamnionitis among US obstetricians. Study Design. We distributed a mail-based survey to members of the American College of Obstetricians and Gynecologists, querying demographics, practice setting, and chorioamnionitis management strategies. We performed univariable and multivariable analyses. Results. Of 500 surveys distributed, 53.8% were returned, and 212 met study criteria and were analyzed. Most respondents work in group practice (66.0%), perform >100 deliveries per year (60.0%), have been in practice >10 years (77.3%), and work in a nonuniversity setting (85.1%). Temperature plus one additional criterion (61.3%) was the most common diagnostic strategy. Over 25 different primary antibiotic regimens were reported, including use of a single agent by 30.0% of respondents. A wide range of postpartum antibiotic duration was reported from no postpartum treatment (34.5% after vaginal delivery, 11.3% after cesarean delivery) to 48 hours of postpartum treatment (24.7% after vaginal delivery, 32.1% after cesarean delivery). No practitioner characteristic was independently associated with diagnostic or therapeutic strategies in multivariable analysis. Conclusion. There is a wide variation in contemporary clinical practices for the management of chorioamnionitis. This may represent a dearth of level I evidence. Future prospective clinical trials may provide more evidence-based practice recommendations for diagnosis and treatment of chorioamnionitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.