Evidence map›Paper›PMID 23319057›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2013

RETRACTED: Insulin-like growth factor-binding protein-7 (IGFBP7): a promising gene therapeutic for hepatocellular carcinoma (HCC).

Dong Chen, Ayesha Siddiq, Luni Emdad, Devaraja Rajasekaran, Rachel Gredler, Xue-Ning Shen, Prasanna K Santhekadur, Jyoti Srivastava, Chadia L Robertson, Igor Dmitriev and 4 more

RetractedErratum issuedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
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  11. Anti-Metastatic and Anti-Angiogenic Activities of Core-Shell SiOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2016
    Article
  12. Article
  13. Pancreatic cancer cell-derived IGFBP-3 contributes to muscle wasting.Journal of experimental & clinical cancer research : CR · 2016
    Article
  14. Article
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  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Dong ChenDepartment of Pathology, Virginia Commonwealth University, School of Medicine, Richmond, Virginia 23298, USA.
Ayesha Siddiq
Luni Emdad
Devaraja Rajasekaran
Rachel Gredler
Xue-Ning Shen
Prasanna K Santhekadur
Jyoti Srivastava
Chadia L Robertson
Igor Dmitriev
Elena A Kashentseva
David T Curiel
Paul B Fisher
Devanand Sarkar
Virginia Commonwealth University · USWashington University in St. Louis · US

Funding

Analysis of a novel regulator of hepatocellular carcinomaR01CA138540 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI SARKAR, DEVANAND · 2010 to 2014
$1.6M
AEG-1: Novel Gene Involved in Malignant GliomaR01CA134721 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI FISHER, PAUL B · 2009 to 2013
$1.5M
NCI NIH HHS R01 CA134721NCI NIH HHS R01 CA138540
6 · The paper itself

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the editor-in-chief. Similarities were found between images within this article. Image analysis performed by the editorial office confirmed findings of image duplication in Figures 1B, 4, and 8A. This reuse (and in part misrepresentation) of data without appropriate attribution represents a severe abuse of the scientific publishing system. No authors responded when contacted about the retraction.

Indexed as

AdenoviridaeAnimalsCarcinoma, HepatocellularHumansInsulin-Like Growth Factor Binding ProteinsLiver NeoplasmsMaleMiceMice, NudeReactive Oxygen SpeciesXenograft Model Antitumor Assaysinsulin-like growth factor binding protein-related protein 1Insulin-Like Growth Factor Binding ProteinsReactive Oxygen Species

Identifiers

PMID23319057
PMCPMC3616543
OpenAlexW2051745191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.