ArticleAntimicrobial agents and chemotherapy2013
Involvement of MarR and YedS in carbapenem resistance in a clinical isolate of Escherichia coli from China.
Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Potential role of avibactam in restoring susceptibility in Escherichia coli with two copies of blaScientific reports · 2025Article
- Development of a logic regression-based approach for the discovery of host- and niche-informative biomarkers inApplied and environmental microbiology · 2024Article
- The Mar, Sox, and Rob Systems.EcoSal Plus · 2023Review
- Antimicrobial Resistance Surveillance of Tigecycline-Resistant Strains Isolated from Herbivores in Northwest China.Microorganisms · 2022Article
- Carbapenem Resistance among Marine Bacteria-An Emerging Threat to the Global Health Sector.Microorganisms · 2021Review
- Deskilled and Rapid Drug-Resistant Gene Detection by Centrifugal Force-Assisted Thermal Convection PCR Device.Sensors (Basel, Switzerland) · 2021Article
- Detection of New Delhi Metallo-β-lactamase 1 and Cephalosporin Resistance Genes Among Carbapenem-Resistant Enterobacteriaceae in Water Bodies Adjacent to Hospitals in India.Current microbiology · 2020Article
- Urban and agricultural soils in Southern California are a reservoir of carbapenem-resistant bacteria.MicrobiologyOpen · 2020Article
- Prevalence and characterization of carbapenem-resistant bacteria in water bodies in the Los Angeles-Southern California area.MicrobiologyOpen · 2019Article
- Structural Alteration of OmpR as a Source of Ertapenem Resistance in a CTX-M-15-Producing Escherichia coli O25b:H4 Sequence Type 131 Clinical Isolate.Antimicrobial agents and chemotherapy · 2017Article
- Tigecycline Nonsusceptibility Occurs Exclusively in Fluoroquinolone-Resistant Escherichia coli Clinical Isolates, Including the Major Multidrug-Resistant Lineages O25b:H4-ST131-H30R and O1-ST648.Antimicrobial agents and chemotherapy · 2017Article
- Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products.Bioorganic & medicinal chemistry · 2016Article
- The rapid spread of carbapenem-resistant Enterobacteriaceae.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2016Review
- Identification of a novel NDM variant, NDM-13, from a multidrug-resistant Escherichia coli clinical isolate in Nepal.Antimicrobial agents and chemotherapy · 2015Article
- Prediction of resistance development against drug combinations by collateral responses to component drugs.Science translational medicine · 2014Article
- Resistance determinants and mobile genetic elements of an NDM-1-encoding Klebsiella pneumoniae strain.PloS one · 2014Article
- Amino acid residues involved in inactivation of the Escherichia coli multidrug resistance repressor MarR by salicylate, 2,4-dinitrophenol, and plumbagin.FEMS microbiology letters · 2013Article
- Mutational analysis of the multiple-antibiotic resistance regulator MarR reveals a ligand binding pocket at the interface between the dimerization and DNA binding domains.Journal of bacteriology · 2013Article
- MarA, SoxS and Rob ofInternational journal of biotechnology for wellness industries · 2013Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
A carbapenem-resistant clinical isolate of Escherichia coli, which lacked OmpF and OmpC porins, carried a marR mutation and expressed a functional yedS, a normally nontranslated gene. MarR and YedS are described here as having effects on the ability of this strain to resist carbapenems. Additionally, expression of YedS was regulated by the small RNA MicF in a MarA-dependent way. These findings illustrate how broadly bacteria can mutate within a selective clinical setting, in this case, resistance to carbapenems, by altering three porin genes and one regulatory gene.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.