Evidence map›Paper›PMID 23318795›Full record

ArticleAntimicrobial agents and chemotherapy2013

The novel CTX-M-116 β-lactamase gene discovered in Proteus mirabilis is composed of parts of the CTX-M-22 and CTX-M-23 genes.

N Fursova, S Pryamchuk, A Kruglov, I Abaev, E Pecherskikh, N Kartsev, E Svetoch, I Dyatlov

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Generation of the blaCTX-M-116 hybrid gene.Antimicrobial agents and chemotherapy · 2013
    Article
  3. Reply to "Generation of the blaCTX-M-116 hybrid gene".Antimicrobial agents and chemotherapy · 2013
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

N FursovaThe State Research Center for Applied Microbiology & Biotechnology, Obolensk, Russia. fursova@obolensk.org
S Pryamchuk
A Kruglov
I Abaev
E Pecherskikh
N Kartsev
E Svetoch
I Dyatlov
State Research Center for Applied Microbiology and Biotechnology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel β-lactamase gene bla(CTX-M-116) was identified in a Proteus mirabilis nosocomial isolate recovered from the urine of a patient in Moscow in 2005. DNA sequence analysis showed bla(CTX-M-116) to be a hybrid gene consisting of 5' bla(CTX-M-23) (nucleotides 1 to 278) and 3' bla(CTX-M-22) (nucleotides 286 to 876) moieties separated by an intervening putative site of recombination (GTTAAAT). A retrospective analysis of available bla(CTX-M) genes in the GenBank database revealed 19 bla(CTX-M) genes that display the same hybrid structure.

Indexed as

Base Sequencebeta-Lactamasesbeta-Lactam Resistancebeta-LactamsCross InfectionDatabases, Nucleic AcidEscherichia coliEscherichia coli ProteinsHumansMolecular Sequence DataProtein IsoformsProteus InfectionsProteus mirabilisRecombination, GeneticSequence Homology, Nucleic Acidbeta-lactamase CTX-M-22, E colibeta-lactamase CTX-M-23, E colibeta-Lactamasesbeta-LactamsEscherichia coli ProteinsProtein Isoforms

Identifiers

PMID23318795
PMCPMC3591887
OpenAlexW2073419007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.