ArticleDevelopment (Cambridge, England)2013
Evidence for dynamic rearrangements but lack of fate or position restrictions in premigratory avian trunk neural crest.
Article in Development (Cambridge, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Article
- Article
- Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination.bioRxiv : the preprint server for biology · 2024Article
- Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma.bioRxiv : the preprint server for biology · 2023Article
- Single-cell transcriptomic analysis of zebrafish cranial neural crest reveals spatiotemporal regulation of lineage decisions during development.Cell reports · 2021Article
- From Neural Crest to Definitive Roof Plate: The Dynamic Behavior of the Dorsal Neural Tube.International journal of molecular sciences · 2021Review
- Cardiac Neural Crest Cells: Their Rhombomeric Specification, Migration, and Association with Heart and Great Vessel Anomalies.Cellular and molecular neurobiology · 2021Review
- Neural crest multipotency and specification: power and limits of single cell transcriptomic approaches.Faculty reviews · 2021Review
- On the road again: Establishment and maintenance of stemness in the neural crest from embryo to adulthood.Stem cells (Dayton, Ohio) · 2021Review
- Development of the Autonomic Nervous System: Clinical Implications.Seminars in neurology · 2020Review
- Establishment of a murine culture system for modeling the temporal progression of cranial and trunk neural crest cell differentiation.Disease models & mechanisms · 2018Article
- From proliferation to target innervation: signaling molecules that direct sympathetic nervous system development.Cell and tissue research · 2018Review
- DAN (NBL1) promotes collective neural crest migration by restraining uncontrolled invasion.The Journal of cell biology · 2017Article
- Illuminating developmental biology through photochemistry.Nature chemical biology · 2017Article
- Article
- Article
- Analysis of neural crest-derived clones reveals novel aspects of facial development.Science advances · 2016Article
- Prospect of Human Pluripotent Stem Cell-Derived Neural Crest Stem Cells in Clinical Application.Stem cells international · 2016Review
- Epithelial-Mesenchymal Transitions during Neural Crest and Somite Development.Journal of clinical medicine · 2015Review
- TrkB/BDNF signalling patterns the sympathetic nervous system.Nature communications · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Neural crest (NC) cells emerge from the dorsal trunk neural tube (NT) and migrate ventrally to colonize neuronal derivatives, as well as dorsolaterally to form melanocytes. Here, we test whether different dorsoventral levels in the NT have similar or differential ability to contribute to NC cells and their derivatives. To this end, we precisely labeled NT precursors at specific dorsoventral levels of the chick NT using fluorescent dyes and a photoconvertible fluorescent protein. NT and NC cell dynamics were then examined in vivo and in slice culture using two-photon and confocal time-lapse imaging. The results show that NC precursors undergo dynamic rearrangements within the neuroepithelium, yielding an overall ventral to dorsal movement toward the midline of the NT, where they exit in a stochastic manner to populate multiple derivatives. No differences were noted in the ability of precursors from different dorsoventral levels of the NT to contribute to NC derivatives, with the exception of sympathetic ganglia, which appeared to be 'filled' by the first population to emigrate. Rather than restricted developmental potential, however, this is probably due to a matter of timing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.