Evidence map›Paper›PMID 23317303›Full record

ReviewAnnals of the New York Academy of Sciences2013

Human adipose dynamics and metabolic health.

Bin Feng, Tracy Zhang, Haiyan Xu

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Annals of the New York Academy of Sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05973526 (Comparative Acute Effects of the Application of Percutaneous and Transcutaneous Electrolipolysis on the Female Abdominal Contour), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05973526 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Comparative Acute Effects of the Application of Percutaneous and Transcutaneous Electrolipolysis on the Female Abdominal Contour: a Cross Over Clinical Trial

TypeinterventionalSponsorUniversidade Federal de PernambucoRan2023 to 2024Enrolled20ConditionsAbdominal FatArmsPercutaneous Electrolipolysis, Transcutaneous Electrolipolysis
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Is Adipose Tissue Inflammation the Culprit of Obesity-Associated Comorbidities?Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Review
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  20. Brown but not white adipose cells synthesize omega-3 docosahexaenoic acid in culture.Prostaglandins, leukotrienes, and essential fatty acids · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bin FengHallett Center for Diabetes and Endocrinology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Tracy Zhang
Haiyan Xu
Brown University · USAmerican Society of Genealogists · US

Funding

MAP Kinase Phosphatase 3 (MKP-3) and Obesity-related GluconeogenesisR01DK080746 · NIDDK · RHODE ISLAND HOSPITAL · PI XU, HAIYAN · 2009 to 2013
$1.7M
NIDDK NIH HHS R01 DK080746NIDDK NIH HHS R01-DK 080746
6 · The paper itself

Abstract

The two types of adipose tissue in humans, white and brown, have distinct developmental origins and functions. Human white adipose tissue plays a pivotal role in maintaining whole-body energy homeostasis by storing triglycerides when energy is in surplus, releasing free fatty acids as a fuel during energy shortage, and secreting adipokines that are important for regulating lipid and glucose metabolism. The size of white adipose mass needs to be kept at a proper set point. Dramatic expansion of white fat mass causes obesity--now become a global epidemic disease--and increases the risk for the development of many life-threatening diseases. The absence of white adipose tissue or abnormal white adipose tissue redistribution leads to lipodystrophy, a condition often associated with metabolic disorders. Brown adipose tissue is a thermogenic organ whose mass is inversely correlated with body mass index and age. Therapeutic approaches targeting adipose tissue have been proven to be effective in improving obesity-related metabolic disorders, and promising new therapies could be developed in the near future.

Indexed as

Health StatusAdipose TissueAnimalsEnergy MetabolismHumansObesity

Identifiers

PMID23317303
PMCPMC3618577
OpenAlexW2136224352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.