ArticleCurrent molecular imaging2012
Strategies for Target-Specific Contrast Agents for Magnetic Resonance Imaging.
Article in Current molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Nanomaterial-Based Precision Drug Delivery for Advanced Nephrology Therapy: A Systematic Review.International journal of nanomedicine · 2026Pooled it
- Organic functionality in responsive paramagnetic nanostructures.Frontiers in chemistry · 2025Review
- The role of responsive MRI probes in the past and the future of molecular imaging.Chemical science · 2024Review
- Decoration of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) with N-oxides increases the TChemistryOpen · 2024Article
- Peptide-Based Agents for Cancer Treatment: Current Applications and Future Directions.International journal of molecular sciences · 2023Review
- Synthesis and characterization of GdScientific reports · 2023Article
- Current update on nanoplatforms as therapeutic and diagnostic tools: A review for the materials used as nanotheranostics and imaging modalities.Asian journal of pharmaceutical sciences · 2021Review
- Simultaneous molecular MRI of extracellular matrix collagen and inflammatory activity to predict abdominal aortic aneurysm rupture.Scientific reports · 2020Article
- Advances in Medical Imaging: Aptamer- and Peptide-Targeted MRI and CT Contrast Agents.ACS omega · 2020Review
- The Continuing Evolution of Molecular Functional Imaging in Clinical Oncology: The Road to Precision Medicine and Radiogenomics (Part II).Molecular diagnosis & therapy · 2019Review
- Myelin-targeted, texaphyrin-based multimodal imaging agent for magnetic resonance and optical imaging.Contrast media & molecular imaging · 2016Article
- Aqueous Lanthanide Chemistry in Asymmetric Catalysis and Magnetic Resonance Imaging.Synlett : accounts and rapid communications in synthetic organic chemistry · 2016Article
- Overcoming the concentration-dependence of responsive probes for magnetic resonance imaging.Metallomics : integrated biometal science · 2015Review
- Recent advances in molecular magnetic resonance imaging of liver fibrosis.BioMed research international · 2015Review
- Effect of lanthanide complex structure on cell viability and association.Inorganic chemistry · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
This review describes recent research efforts focused on increasing the specificity of contrast agents for proton magnetic resonance imaging (MRI). Contrast agents play an indispensable role in MRI by enhancing the inherent contrast of images; however, the non-specific nature of current clinical contrast agents limits their usefulness. This limitation can be addressed by conjugating contrast agents or contrast-agent-loaded carriers-including polymers, nanoparticles, dendrimers, and liposomes-to molecules that bind to biological sites of interest. An alternative approach to conjugation is synthetically mimicking biological structures with metal complexes that are also contrast agents. In this review, we describe the advantages and limitations of these two targeting strategies with respect to translation from in vitro to in vivo imaging while focusing on advances from the last ten years.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.