ArticleG3 (Bethesda, Md.)2013
Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-repentis, reveals transduplication and the impact of repeat elements on pathogenicity and population divergence.
Article in G3 (Bethesda, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
81 citing papers in PubMed, 178 citations in OpenAlex.
- Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi.Angewandte Chemie (International ed. in English) · 2025Article
- CoreDetector: a flexible and efficient program for core-genome alignment of evolutionary diverse genomes.Bioinformatics (Oxford, England) · 2023Article
- Spatiotemporal patterns of wheat response to Pyrenophora tritici-repentis in asymptomatic regions revealed by transcriptomic and X-ray fluorescence microscopy analyses.Journal of experimental botany · 2023Article
- Prediction of effector protein structures from fungal phytopathogens enables evolutionary analyses.Nature microbiology · 2023Article
- Cytospora paraplurivora sp. nov. isolated from orchards with fruit tree decline syndrome in Ontario, Canada.PloS one · 2023Article
- How do emerging long-read sequencing technologies function in transforming the plant pathology research landscape?Plant molecular biology · 2022Review
- The pangenome of the wheat pathogen Pyrenophora tritici-repentis reveals novel transposons associated with necrotrophic effectors ToxA and ToxB.BMC biology · 2022Article
- A global pangenome for the wheat fungal pathogenMicrobial genomics · 2022Article
- Phylogenetic Comparison of Swainsonine Biosynthetic Gene Clusters among Fungi.Journal of fungi (Basel, Switzerland) · 2022Article
- Genome-Wide Association Study for Resistance to Tan Spot in Synthetic Hexaploid Wheat.Plants (Basel, Switzerland) · 2022Article
- Comparative Genomics of ThreeFrontiers in microbiology · 2022Article
- Review
- Genetic characterization of adult-plant resistance to tan spot (syn, yellow spot) in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- The first genome assembly of fungal pathogen Pyrenophora tritici-repentis race 1 isolate using Oxford Nanopore MinION sequencing.BMC research notes · 2021Article
- Article
- Increased abundance of secreted hydrolytic enzymes and secondary metabolite gene clusters define the genomes of latent plant pathogens in the Botryosphaeriaceae.BMC genomics · 2021Article
- Genetic Relationships in the Toxin-Producing Fungal Endophyte,Journal of fungi (Basel, Switzerland) · 2021Article
- Rapid sequence evolution driven by transposable elements at a virulence locus in a fungal wheat pathogen.BMC genomics · 2021Article
- Article
- Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
26 authors at 14 institutions in 4 countries.
Funding
Abstract
Pyrenophora tritici-repentis is a necrotrophic fungus causal to the disease tan spot of wheat, whose contribution to crop loss has increased significantly during the last few decades. Pathogenicity by this fungus is attributed to the production of host-selective toxins (HST), which are recognized by their host in a genotype-specific manner. To better understand the mechanisms that have led to the increase in disease incidence related to this pathogen, we sequenced the genomes of three P. tritici-repentis isolates. A pathogenic isolate that produces two known HSTs was used to assemble a reference nuclear genome of approximately 40 Mb composed of 11 chromosomes that encode 12,141 predicted genes. Comparison of the reference genome with those of a pathogenic isolate that produces a third HST, and a nonpathogenic isolate, showed the nonpathogen genome to be more diverged than those of the two pathogens. Examination of gene-coding regions has provided candidate pathogen-specific proteins and revealed gene families that may play a role in a necrotrophic lifestyle. Analysis of transposable elements suggests that their presence in the genome of pathogenic isolates contributes to the creation of novel genes, effector diversification, possible horizontal gene transfer events, identified copy number variation, and the first example of transduplication by DNA transposable elements in fungi. Overall, comparative analysis of these genomes provides evidence that pathogenicity in this species arose through an influx of transposable elements, which created a genetically flexible landscape that can easily respond to environmental changes.
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Registered trials
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