ArticleG3 (Bethesda, Md.)2013
Strategies for outcrossing and genetic manipulation of Drosophila compound autosome stocks.
Article in G3 (Bethesda, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- The Cell Biology of Heterochromatin.Cells · 2022Review
- A Simplified Strategy for Introducing Genetic Variants intoG3 (Bethesda, Md.) · 2016Article
- Waves of Cdk1 Activity in S Phase Synchronize the Cell Cycle in Drosophila Embryos.Developmental cell · 2016Article
- Aurora B-mediated localized delays in nuclear envelope formation facilitate inclusion of late-segregating chromosome fragments.Molecular biology of the cell · 2015Article
- Behavior of aberrant chromosome configurations in Drosophila melanogaster female meiosis I.G3 (Bethesda, Md.) · 2014Article
- Centromere-independent accumulation of cohesin at ectopic heterochromatin sites induces chromosome stretching during anaphase.PLoS biology · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Among all organisms, Drosophila melanogaster has the most extensive well-characterized collection of large-scale chromosome rearrangements. Compound chromosomes, rearrangements in which homologous chromosome arms share a centromere, have proven especially useful in genetic-based surveys of the entire genome. However, their potential has not been fully realized because compound autosome stocks are refractile to standard genetic manipulations: if outcrossed, they yield inviable aneuploid progeny. Here we describe two strategies, cold-shock and use of the bubR1 mutant alleles, to produce nullo gametes through nondisjunction. These gametes are complementary to the compound chromosome-bearing gametes and thus produce viable progeny. Using these techniques, we created a compound chromosome two C(2)EN stock bearing a red fluorescent protein-histone transgene, facilitating live analysis of these unusually long chromosomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.