ArticleFrontiers in immunology2012
New views of the human NK cell immunological synapse: recent advances enabled by super- and high-resolution imaging techniques.
Article in Frontiers in immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- The membrane distal domain of CD16a allosterically regulates NK cell ADCC.bioRxiv : the preprint server for biology · 2026Article
- MINFLUX nanoscopy to study the NK cell immune synapse.Methods in cell biology · 2026Article
- Microtubule regulation in cancer cells.Frontiers in cell and developmental biology · 2025Article
- Spatially resolved in silico modeling of NKG2D signaling kinetics suggests a key role of NKG2D and Vav1 Co-clustering in generating natural killer cell activation.PLoS computational biology · 2022Article
- Engineering Anti-Tumor Monoclonal Antibodies and Fc Receptors to Enhance ADCC by Human NK Cells.Cancers · 2021Review
- The Right Partner in Crime: Unlocking the Potential of the Anti-EGFR Antibody CetuximabFrontiers in immunology · 2021Review
- AlternativeFrontiers in immunology · 2020Article
- Considerations of Antibody Geometric Constraints on NK Cell Antibody Dependent Cellular Cytotoxicity.Frontiers in immunology · 2020Review
- An actin cytoskeletal barrier inhibits lytic granule release from natural killer cells in patients with Chediak-Higashi syndrome.The Journal of allergy and clinical immunology · 2018Observational
- Laboratory cryo x-ray microscopy for 3D cell imaging.Scientific reports · 2017Article
- Molecular Imaging: A Useful Tool for the Development of Natural Killer Cell-Based Immunotherapies.Frontiers in immunology · 2017Review
- High- and Super-Resolution Microscopy Imaging of the NK Cell Immunological Synapse.Methods in molecular biology (Clifton, N.J.) · 2016Article
- Dances with Membranes: Breakthroughs from Super-resolution Imaging.Current topics in membranes · 2015Review
- MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress.Molecular cancer · 2014Review
- Visualization of the immunological synapse by dual color time-gated stimulated emission depletion (STED) nanoscopy.Journal of visualized experiments : JoVE · 2014Article
- In vivo administration of a JAK3 inhibitor during acute SIV infection leads to significant increases in viral load during chronic infection.PLoS pathogens · 2014Article
- Live-cell imaging of receptors around postsynaptic membranes.Nature protocols · 2014Article
- Article
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2 authors.
Funding
Abstract
Imaging technology has undergone rapid growth with the development of super resolution microscopy, which enables resolution below the diffraction barrier of light (~200 nm). In addition, new techniques for single molecule imaging are being added to the cell biologist's arsenal. Immunologists have exploited these techniques to advance understanding of NK biology, particularly that of the immune synapse. The immune synapse's relatively small size and complex architecture combined with its exquisitely controlled signaling milieu have made it a challenge to visualize. In this review we highlight and discuss new insights into NK cell immune synapse formation and regulation revealed by cutting edge imaging techniques, including super-resolution microscopy, high-resolution total internal reflection microscopy, and Förster resonance energy transfer.
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