Evidence map›Paper›PMID 23315743›Full record

ArticleApplied and environmental microbiology2013

Characterization of an acid-inducible sulfatase in Salmonella enterica serovar typhimurium.

Seema Das, Swati Singh, Michael McClelland, Steven Forst, Prasad Gyaneshwar

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Seema DasDepartment of Biological Sciences, University of Wisconsin Milwaukee, Milwaukee, Wisconsin, USA.
Swati Singh
Michael McClelland
Steven Forst
Prasad Gyaneshwar
University of Wisconsin–Milwaukee · USUniversity of California, Irvine · US

Funding

NITRIC OXIDE CYTOTOXICITY IN SALMONELLOSISR01AI039557 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 1997 to 2012
$4.1M
Comparative Genomics in the EnterobateriaceaeR01AI052237 · NIAID · WASHINGTON UNIVERSITY · PI WEINSTOCK, GEORGE M · 2002 to 2009
$4.1M
Salmonella polymicrobial interactionsR01AI073971 · NIAID · OHIO STATE UNIVERSITY · PI AHMER, BRIAN M · 2008 to 2012
$2.8M
Identification of Salmonella Genes Important for Systemic ColonizationR01AI083646 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ANDREWS-POLYMENIS, HELENE L · 2009 to 2012
$1.6M
Salmonella Genes Associated with Colonization of Specific HostsR01AI075093 · NIAID · VACCINE RESEARCH INSTITUTE OF SAN DIEGO · PI MCCLELLAND, MICHAEL · 2009 to 2010
$928k
Identification of Salmonella Genes Involved in Persistence in the Murine IntestinR56AI077645 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ANDREWS-POLYMENIS, HELENE L · 2009 to 2009
$423k
MECHANISMS OF NITRIC OXIDE CYTOTOXICITY IN SALMONELLOSISR21AI039557 · NIAID · UNIVERSITY OF COLORADO DENVER · PI FANG, FERRIC C · 1996 to 1996
–
NIAID NIH HHS AI039557NIAID NIH HHS AI052237NIAID NIH HHS AI073971NIAID NIH HHS AI075093NIAID NIH HHS AI077645NIAID NIH HHS AI083646NIAID NIH HHS R01 AI039557NIAID NIH HHS R01 AI052237NIAID NIH HHS R01 AI073971NIAID NIH HHS R01 AI075093NIAID NIH HHS R01 AI083646NIAID NIH HHS R56 AI077645
6 · The paper itself

Abstract

Sulfatases of enteric bacteria can provide access to heavily sulfated mucosal glycans. In this study, we show that aslA (STM0084) of Salmonella enterica serovar Typhimurium LT2 encodes a sulfatase that requires mildly acidic pH for its expression and activity. AslA is not regulated by sulfur compounds or tyramine but requires the EnvZ-OmpR and PhoPQ regulatory systems, which play an important role in pathogenesis.

Indexed as

Transcriptional ActivationAcidsBacterial ProteinsGene Expression Regulation, BacterialHydrogen-Ion ConcentrationSalmonella typhimuriumSulfatasesAcidsBacterial ProteinsSulfatases

Identifiers

PMID23315743
PMCPMC3592217
OpenAlexW2111502814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.