ArticleThe Plant cell2013
Arabidopsis chromatin remodeling factor PICKLE interacts with transcription factor HY5 to regulate hypocotyl cell elongation.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
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Who cites it
89 citing papers in PubMed, 183 citations in OpenAlex.
- Linking cellular metabolism to chromatin modifications in plants.Journal of integrative plant biology · 2026Review
- Functional Characterisation of NF-YCs in True Leaf Biomass Accumulation.Plants (Basel, Switzerland) · 2026Article
- TCP21 negatively regulates photomorphogenesis by integrating phyB- and HY5-mediated signaling pathways in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- Conserved DNA architect couples chloroplast development to cell cycle in developing cotyledons.Nature plants · 2026Article
- Static Magnetic Field Promotes Wheat Nitrogen Assimilation by Repressing Jasmonates Biosynthesis Through TaHY5.Plant biotechnology journal · 2026Article
- Single-molecule views of chromatin accessibility and structure during photomorphogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- PKL mediates H3K4me2 modification and spatial gene congregation in chromatin regulation.Nucleic acids research · 2025Article
- PagKNAT5a promotes plant growth by enhancing xylem cell elongation and secondary wall formation in poplar.Horticulture research · 2025Article
- TheProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Review
- The cotton MYB33 gene is a hub gene regulating the trade-off between plant growth and defense in Verticillium dahliae infection.Journal of advanced research · 2024Article
- In silico analysis identified bZIP transcription factors genes responsive to abiotic stress in Alfalfa (Medicago sativa L.).BMC genomics · 2024Article
- Article
- Article
- Study on the Degradation of Methylene Blue by Cu-Doped SnSe.Molecules (Basel, Switzerland) · 2023Article
- Condensation of SEUSS promotes hyperosmotic stress tolerance in Arabidopsis.Nature chemical biology · 2022Article
- The RNA helicase UAP56 and the E3 ubiquitin ligase COP1 coordinately regulate alternative splicing to repress photomorphogenesis in Arabidopsis.The Plant cell · 2022Article
- Induced mutation in ELONGATED HYPOCOTYL5 abolishes anthocyanin accumulation in the hypocotyl of pepper.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Light, chromatin, action: nuclear events regulating light signaling in Arabidopsis.The New phytologist · 2022Review
- The transcriptional repressors VAL1 and VAL2 mediate genome-wide recruitment of the CHD3 chromatin remodeler PICKLE in Arabidopsis.The Plant cell · 2022Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photomorphogenesis is a critical plant developmental process that involves light-mediated transcriptome changes, histone modifications, and inhibition of hypocotyl growth. However, the chromatin-based regulatory mechanism underlying this process remains largely unknown. Here, we identify ENHANCED PHOTOMORPHOGENIC1 (EPP1), previously known as PICKLE (PKL), an ATP-dependent chromatin remodeling factor of the chromodomain/helicase/DNA binding family, as a repressor of photomorphogenesis in Arabidopsis thaliana. We show that PKL/EPP1 expression is repressed by light in the hypocotyls in a photoreceptor-dependent manner. Furthermore, we reveal that the transcription factor ELONGATED HYPOCOTYL5 (HY5) binds to the promoters of cell elongation-related genes and recruits PKL/EPP1 through their physical interaction. PKL/EPP1 in turn negatively regulates HY5 by repressing trimethylation of histone H3 Lys 27 at the target loci, thereby regulating the expression of these genes and, thus, hypocotyl elongation. We also show that HY5 possesses transcriptional repression activity. Our study reveals a crucial role for a chromatin remodeling factor in repressing photomorphogenesis and demonstrates that transcription factor-mediated recruitment of chromatin-remodeling machinery is important for plant development in response to changing light environments.
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