ArticleJournal of experimental botany2013
ML3: a novel regulator of herbivory-induced responses in Arabidopsis thaliana.
Article in Journal of experimental botany, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Impact of Lepidopteran Oral Secretions on the Transcriptome ofPlant direct · 2025Article
- Ectopic expression of a truncated NLR gene from wildFrontiers in plant science · 2024Article
- Establishment and application of a root wounding-immersion method for efficient virus-induced gene silencing in plants.Frontiers in plant science · 2024Article
- An MD-2-related lipid-recognition protein is required for insect reproduction and integument development.Open biology · 2021Article
- Arabidopsis Response to Inhibitor of Cytokinin Degradation INCYDE: Modulations of Cytokinin Signaling and Plant Proteome.Plants (Basel, Switzerland) · 2020Article
- Insights into the molecular basis of biocontrol of Brassica pathogens by Bacillus amyloliquefaciens UCMB5113 lipopeptides.Annals of botany · 2017Article
- RabGAP22 is required for defense to the vascular pathogen Verticillium longisporum and contributes to stomata immunity.PloS one · 2014Article
- ML3 is a NEDD8- and ubiquitin-modified protein.Plant physiology · 2013Article
- Understanding plant defence responses against herbivore attacks: an essential first step towards the development of sustainable resistance against pests.Transgenic research · 2013Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ML (MD2-related lipid recognition) proteins are known to enhance innate immune responses in mammals. This study reports the analysis of the putative ML gene family in Arabidopsis thaliana and suggests a role for the ML3 gene in herbivory-associated responses in plants. Feeding by larvae of the Lepidopteran generalist herbivore Spodoptera littoralis and larvae of the specialist herbivore Plutella xylostella activated ML3 transcription in leaf tissues. ML3 loss-of-function Arabidopsis plants were compromised in the upregulation of herbivory-induced genes and displayed a semi-dwarf phenotype. Herbivory bioassays showed that larvae of S. littoralis fed on ml3 mutant plants gained more weight compared to larvae fed on wild-type plants while larvae of P. xylostella did not show any significant difference. Virus-induced gene silencing of ML3 expression in plants compromised in jasmonic acid (JA) and salicylic acid (SA) signalling revealed a complex role of ML3 in JA/defence signalling affecting both JA- and SA-dependent responses. The data suggest that ML3 is involved in herbivory-mediated responses in Arabidopsis and that it has a potential role in herbivory-associated molecular pattern recognition.
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Registered trials
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