Evidence map›Paper›PMID 23314684›Full record

ArticleEuropean journal of applied physiology2013

Maintained cerebrovascular function during post-exercise hypotension.

Christopher K Willie, Philip N Ainslie, Chloe E Taylor, Neil D Eves, Yu-Chieh Tzeng

Abstract read
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Article in European journal of applied physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 31 citations in OpenAlex.

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  12. Pathophysiology of Noncardiac Syncope in Athletes.Sports medicine (Auckland, N.Z.) · 2018
    Review
  13. Article
  14. Article
  15. The cardiovascular system after exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2017
    Review
  16. Article
  17. Article
  18. Integrative regulation of human brain blood flow.The Journal of physiology · 2014
    Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Christopher K WillieCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, 3333 University Way, Okanagan, Kelowna, BC, Canada. ckwillie@gmail.com
Philip N Ainslie
Chloe E Taylor
Neil D Eves
Yu-Chieh Tzeng
University of British Columbia · CALiverpool John Moores University · GBOkanagan University College · CAUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The post-exercise period is associated with hypotension, and an increased risk of syncope attributed to decreases in venous return and/or vascular resistance. Increased local and systemic vasodilators, sympatholysis, and attenuated baroreflex sensitivity following exercise are also manifest. Although resting cerebral blood flow is maintained, cerebrovascular regulation to acute decreases in blood pressure has not been characterized following exercise. We therefore aimed to assess cerebrovascular regulation during transient bouts of hypotension, before and after 40 min of aerobic exercise at 60 % of estimated maximum oxygen consumption. Beat to beat blood pressure (Finometer), heart rate (ECG), and blood velocity in the middle cerebral artery (MCAv; transcranial Doppler ultrasound) were assessed in ten healthy young humans. The MCAv-mean arterial pressure relationship during a pharmacologically (i.v. sodium nitroprusside) induced transient hypotension was assessed before and at 10, 30, and 60 min following exercise. Despite a significant reduction in mean arterial pressure at 10 min post-exercise (-10 ± 6.9 mmHg; P < 0.05) and end-tidal PCO2 (10 min post: -2.9 ± 2.6 mmHg; 30 min post: -3.9 ± 3.5 mmHg; 60 min post: -2.7 ± 2.0 mmHg; all P < 0.05), neither resting MCAv nor the cerebrovascular response to hypotension differed between pre- and post-exercise periods (P > 0.05). These data indicate that cerebrovascular regulation remains intact following a moderate bout of aerobic exercise.

Indexed as

Cerebrovascular CirculationAdultBlood PressureExerciseFemaleHeart RateHumansMaleMiddle Cerebral ArteryOxygen ConsumptionPost-Exercise HypotensionUltrasonography

Identifiers

PMID23314684
OpenAlexW1975861606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.