Evidence map›Paper›PMID 23314669›Full record

ArticleJournal of clinical gastroenterology2013

Celiac disease in a child with ulcerative colitis: a possible genetic association.

Sam X Cheng, Aileen Raizner, Uma P Phatak, Judy H Cho, Dinesh S Pashankar

Abstract readCase Reports
In one paragraph

Article in Journal of clinical gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sam X ChengSection of Gastroenterology, Department of Pediatrics, Yale University, New Haven, CT, USA.
Aileen Raizner
Uma P Phatak
Judy H Cho
Dinesh S Pashankar
Yale University · US

Funding

TRAINING PROGRAM IN INVESTIGATIVE GASTROENTEROLOGYT32DK007017 · NIDDK · YALE UNIVERSITY · PI Fred Sanford Gorelick, Liza Konnikova · 1986 to 2026
$7.1M
YALE PEDIATRIC BASIC SCIENCE TRAINING PROGRAMT32HD068201 · NICHD · YALE UNIVERSITY · PI EGAN, MARIE E · 2011 to 2015
$1.3M
NICHD NIH HHS T32 HD068201NIDDK NIH HHS T32 DK007017
6 · The paper itself

Abstract

Celiac disease and inflammatory bowel disease including ulcerative colitis (UC) and Crohn's disease are both immune-mediated enteropathies. It is rare for both celiac disease and inflammatory bowel disease to occur together in an individual patient. This association has been reported in adults, however, very rarely in children. Here, we report an unusual case of an 8-year-old child with a history of anemia and failure to thrive who presented with bloody diarrhea. His evaluation showed anemia, elevated inflammatory markers, and positive celiac antibodies. Endoscopic evaluation revealed partial duodenal villous atrophy and pancolitis. He was diagnosed with celiac disease and UC and responded well to a gluten-free diet and steroid/mesalamine therapy. The patient's genetic testing revealed markers showing susceptibility for both celiac disease and UC. It is important to be aware of this association as both conditions can present with similar clinical features, however, require different therapeutic approaches.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalCeliac DiseaseChildColitis, UlcerativeDiet, Gluten-FreeEndoscopy, GastrointestinalGastrointestinal AgentsGenetic Predisposition to DiseaseGenetic TestingHumansMaleMesalaminePhenotypePredictive Value of TestsProtein Tyrosine Phosphatase, Non-Receptor Type 2Serologic TestsAnti-Inflammatory Agents, Non-SteroidalGastrointestinal AgentsMesalamineProtein Tyrosine Phosphatase, Non-Receptor Type 2PTPN2 protein, humanSteroids

Identifiers

PMID23314669
PMCPMC4425271
OpenAlexW2042273532

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.