Evidence map›Paper›PMID 23314295›Full record

ReviewPediatric research2013

Systems biology approaches to identify developmental bases for lung diseases.

Soumyaroop Bhattacharya, Thomas J Mariani

Open access · bronzeAbstract readReview
In one paragraph

Review in Pediatric research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Time-resolved proteome profiling of normal lung development.American journal of physiology. Lung cellular and molecular physiology · 2018
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The genome-wide transcriptional response to neonatal hyperoxia identifies Ahr as a key regulator.American journal of physiology. Lung cellular and molecular physiology · 2014
    Article
  12. Integrating omics technologies to study pulmonary physiology and pathology at the systems level.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Soumyaroop BhattacharyaDivision of Neonatology and Program in Pediatric Molecular and Personalized Medicine, University of Rochester Medical Center, Rochester, New York, USA.
Thomas J Mariani
University of Rochester Medical Center · US

Funding

Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic PreemiesU01HL101813 · NHLBI · UNIVERSITY OF ROCHESTER · PI MARIANI, THOMAS J, PRYHUBER, GLORIA S · 2010 to 2014
$2.4M
Functional Genomics of AlveogenesisR01HL071885 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MARIANI, THOMAS J · 2003 to 2006
$1.4M
SERPINE2 as a Candidate COPD Susceptibility GeneR21ES014372 · NIEHS · UNIVERSITY OF ROCHESTER · PI MARIANI, THOMAS J · 2007 to 2008
$318k
NHLBI NIH HHS R01 HL071885NHLBI NIH HHS U01 HL101813NIEHS NIH HHS R21 ES014372
6 · The paper itself

Abstract

A greater understanding of the regulatory processes contributing to lung development could be helpful to identify strategies to ameliorate morbidity and mortality in premature infants and to identify individuals at risk for congenital and/or chronic lung diseases. Over the past decade, genomics technologies have enabled the production of rich gene expression databases providing information for all genes across developmental time or in diseased tissue. These data sets facilitate systems biology approaches for identifying underlying biological modules and programs contributing to the complex processes of normal development and those that may be associated with disease states. The next decade will undoubtedly see rapid and significant advances in redefining both lung development and disease at the systems level.

Indexed as

AnimalsDevelopmental BiologyGene Expression ProfilingGene Expression Regulation, DevelopmentalGenomeGenomicsHumansLungLung DiseasesMetabolomicsMiceModels, BiologicalOligonucleotide Array Sequence AnalysisSystems Biology

Identifiers

PMID23314295
PMCPMC3615902
OpenAlexW2013578604

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.