Evidence map›Paper›PMID 23313953›Full record

ArticleNature genetics2013

A heterozygous moth genome provides insights into herbivory and detoxification.

Minsheng You, Zhen Yue, Weiyi He, Xinhua Yang, Guang Yang, Miao Xie, Dongliang Zhan, Simon W Baxter, Liette Vasseur, Geoff M Gurr and 43 more

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Nature genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 257 papers.

0numbers the graph read from it
0cells of the map it votes in
257citing papers in PubMed
25.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

257 citing papers in PubMed, 569 citations in OpenAlex.

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  10. Complex Roles of Insect Cytochrome P450s in Chemical Adaptation.International journal of biological sciences · 2026
    Review
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197 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

53 authors at 10 institutions in 6 countries.

Minsheng YouInstitute of Applied Ecology, Fujian Agriculture and Forestry University, Fuzhou, China. msyou@iae.fjau.edu.cn
Zhen Yue
Weiyi He
Xinhua Yang
Guang Yang
Miao Xie
Dongliang Zhan
Simon W Baxter
Liette Vasseur
Geoff M Gurr
Carl J Douglas
Jianlin Bai
Ping Wang
Kai Cui
Shiguo Huang
Xianchun Li
Qing Zhou
Zhangyan Wu
Qilin Chen
Chunhui Liu
Bo Wang
Xiaojing Li
Xiufeng Xu
Changxin Lu
Min Hu
John W Davey
Sandy M Smith
Mingshun Chen
Xiaofeng Xia
Weiqi Tang
Fushi Ke
Dandan Zheng
Yulan Hu
Fengqin Song
Yanchun You
Xiaoli Ma
Lu Peng
Yunkai Zheng
Yong Liang
Yaqiong Chen
Liying Yu
Younan Zhang
Yuanyuan Liu
Guoqing Li
Lin Fang
Jingxiang Li
Xin Zhou
Yadan Luo
Caiyun Gou
Junyi Wang
Jian Wang
Huanming Yang
Jun Wang
BGI Group (China) · CNFujian Agriculture and Forestry University · CNInstitute of Applied Ecology · CNAgricultural Research Service · USCharles Sturt University · AUCornell University · USUniversity of Arizona · USUniversity of British Columbia · CAUniversity of Cambridge · GBUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

How an insect evolves to become a successful herbivore is of profound biological and practical importance. Herbivores are often adapted to feed on a specific group of evolutionarily and biochemically related host plants, but the genetic and molecular bases for adaptation to plant defense compounds remain poorly understood. We report the first whole-genome sequence of a basal lepidopteran species, Plutella xylostella, which contains 18,071 protein-coding and 1,412 unique genes with an expansion of gene families associated with perception and the detoxification of plant defense compounds. A recent expansion of retrotransposons near detoxification-related genes and a wider system used in the metabolism of plant defense compounds are shown to also be involved in the development of insecticide resistance. This work shows the genetic and molecular bases for the evolutionary success of this worldwide herbivore and offers wider insights into insect adaptation to plant feeding, as well as opening avenues for more sustainable pest management.

Indexed as

Genetic VariationHeterozygotePhylogenyAdaptation, BiologicalAnimalsBase SequenceChinaChromosomes, Artificial, BacterialComputational BiologyEvolution, MolecularExpressed Sequence TagsFemaleGene Expression ProfilingGenomeGlucosinolatesHerbivoryGlucosinolatesSulfatases

Identifiers

PMID23313953
OpenAlexW2119258755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.