Evidence map›Paper›PMID 23313330›Full record

ReviewTrends in cardiovascular medicine2013

Pericytes from human veins for treatment of myocardial ischemia.

Rajesh G Katare, Paolo Madeddu

Open access · greenAbstract readReview
In one paragraph

Review in Trends in cardiovascular medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Fabrication of New Hybrid Scaffolds forFrontiers in cardiovascular medicine · 2020
    Article
  6. Relative contributions of adipose-resident CD146NPJ Regenerative medicine · 2019
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. The Role of MicroRNAs in Cardiac Stem Cells.Stem cells international · 2015
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Rajesh G KatareOtago School of Medical Sciences, University of Otago, Dunedin, New Zealand.
Paolo Madeddu
Bristol Royal Infirmary · GBUniversity of Otago · NZ

Funding

British Heart Foundation PG/10/81/28606Medical Research Council
6 · The paper itself

Abstract

Stem cell therapies promise to regenerate the infarcted heart through the replacement of dead cardiac cells and stimulation of neovascularization. New research from our laboratory shows the transplantation of stem cells from human veins helps heart healing after an acute ischemic insult. Using a mouse model, we demonstrated that pericytes expanded from redundant human leg veins relocate around the vessels of the peri-infarct zone and release factors that promote reparative angiogenesis and cardiomyocyte survival and inhibit interstitial fibrosis. We plan to perform a first-in-man clinical trial with human pericytes in patients with refractory myocardial ischemia in the next 5 years.

Indexed as

RegenerationAnimalsCell SurvivalDisease Models, AnimalFibrosisHumansLower ExtremityMiceMyocardial IschemiaMyocardiumNeovascularization, PhysiologicPericytesVeins

Identifiers

PMID23313330
PMCPMC3616362
OpenAlexW2091357684

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.