Evidence map›Paper›PMID 23312549›Full record

SynthesisSeminars in arthritis and rheumatism2013

Improvement in wrist pain with ultrasound-guided glucocorticoid injections: a meta-analysis of individual patient data.

Maureen Dubreuil, Stephanie Greger, Michael LaValley, Joanna Cunnington, Wilmer L Sibbitt, Eugene Y Kissin

Open access · greenAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Seminars in arthritis and rheumatism, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. General Applications of Ultrasound in Rheumatology Practice.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2015
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Maureen DubreuilDepartment of Rheumatology, Boston Medical Center, Boston, MA 02118, USA. maureen.dubreuil@bmc.org
Stephanie Greger
Michael LaValley
Joanna Cunnington
Wilmer L Sibbitt
Eugene Y Kissin
Boston Medical Center · USBoston University · USRoyal Adelaide Hospital · AUUniversity of New Mexico · US

Funding

WORK DISABILITY-- PERSONS WITH RHEUMATOID ARTHRITISP60AR047785 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2001 to 2016
$18.0M
RHEUMATOLOGY TRAINING GRANTT32AR007598 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 1997 to 2018
$2.3M
NIAMS NIH HHS P60 AR047785NIAMS NIH HHS T32 AR007598
6 · The paper itself

Abstract

objectivesThis meta-analysis compares change in wrist pain following ultrasound-guided (US-guided) intra-articular glucocorticoid injections with change in pain after palpation-guided injections in persons with inflammatory arthritis or osteoarthritis.

methodsData sources included MEDLINE, Cochrane, BIOSIS, CINAHL, ACR/AHRP abstracts, and ClinicalTrials.gov. Studies that assessed change in wrist pain with direct comparison of US-guided and palpation-guided injections were included in the meta-analysis. Subject-level data was sought from authors of all relevant studies. Primary outcome was mean change in wrist pain from baseline to 1-6 week follow-up by visual analog scale (VAS). Mean difference in VAS was calculated for comparative studies. Secondary outcome was proportion attaining Minimal Clinically Important Improvement (MCII), defined as VAS reduction ≥ 20%. Odds ratios (ORs) of MCII were calculated for comparative studies. Mean differences in VAS and ORs for MCII for comparative studies were combined using fixed and random effects meta-analysis.

resultsTen studies were eligible, and adequate data was available from 4 studies with direct comparison of US-guided and palpation-guided treatment arms. The difference in mean VAS reduction (US-guided minus palpation-guided) ranged from-0.2 to 1.3, with a combined estimate of 1.0 (95% CI 0.3, 1.7). OR for MCII in comparative studies ranged from 1.0 to 12.4, with a combined OR of 3.2 (95% CI 1.2, 8.5) in favor of ultrasound.

conclusionsUS-guided glucocorticoid injections to the wrist result in greater reductions in pain, and greater likelihood of attaining MCII than palpation-guided injections at 1-6 weeks follow-up.

Indexed as

ArthralgiaUltrasonography, InterventionalGlucocorticoidsHumansInjections, Intra-ArticularPain ManagementPain MeasurementTreatment OutcomeWrist JointGlucocorticoids

Identifiers

PMID23312549
PMCPMC4146403
OpenAlexW2138610847

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.