Evidence map›Paper›PMID 23312542›Full record

ArticleOral surgery, oral medicine, oral pathology and oral radiology2013

Microbiology and epidemiology of oral yeast colonization in hemopoietic progenitor cell transplant recipients.

Steven D Westbrook, William R Kirkpatrick, Nathan P Wiederhold, Cesar O Freytes, Juan J Toro, Thomas F Patterson, Spencer W Redding

Open access · greenAbstract read
In one paragraph

Article in Oral surgery, oral medicine, oral pathology and oral radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Journal of oral microbiology · 2017
    Article
  6. Oral mucositis caused byTherapeutic advances in infectious disease · 2017
    Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Steven D WestbrookDepartment of Comprehensive Dentistry, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-390, USA. westbrooks@uthscsa.edu
William R Kirkpatrick
Nathan P Wiederhold
Cesar O Freytes
Juan J Toro
Thomas F Patterson
Spencer W Redding
The University of Texas Health Science Center at San Antonio · USSouth Texas Veterans Health Care System · US

Funding

Detection and Significance of Antifungal Resistance in Oropharyngeal CandidiasisR01DE018096 · NIDCR · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI PATTERSON, THOMAS F. · 2006 to 2010
$2.5M
NIDCR NIH HHS DE-18096NIDCR NIH HHS R01 DE018096
6 · The paper itself

Abstract

objectiveWe monitored the epidemiology and microbiology of oral yeast colonization in patients undergoing hemopoietic progenitor cell transplantation (HPCT) to examine associations between yeast colonization and oral mucositis. STUDY

designOne hundred twenty-one consecutive HPCT patients were sampled for oral yeasts prior to fluconazole (FLC) prophylaxis, at transplantation, and weekly until discharge. Clinical oral mucositis screenings were performed triweekly.

resultsYeast colonization was evident at 216 of 510 total visits. Candida albicans and Candida glabrata were the predominant organisms. Eight patients showed elevated minimal inhibitory concentrations to FLC. One patient developed fungal septicemia. Patients with oral mucositis assessment scale scores <20 had higher colonization rates than those with higher scores.

conclusionsFLC is effective in controlling a variety of oral yeasts in HPCT recipients. FLC-resistant yeasts do emerge and can be the source of fungal sepsis. A positive association was not shown between yeast colonization and the presence or severity of oral mucositis.

Indexed as

Hematopoietic Stem Cell TransplantationAdultAgedAntineoplastic Combined Chemotherapy ProtocolsCandidaCandida albicansCandida glabrataCandida tropicalisCandidiasis, OralChemopreventionCohort StudiesDrug Resistance, FungalFemaleFluconazoleFollow-Up StudiesFungemiaFluconazole

Identifiers

PMID23312542
PMCPMC3593808
OpenAlexW2020003392

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.