Evidence map›Paper›PMID 23312085›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2012

Comparison of a fur mite PCR assay and the tape test for initial and posttreatment diagnosis during a natural infection.

Erica E Weiss, Kristin D Evans, Stephen M Griffey

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Safety and efficacy of topical lime sulfur in mice infested with Myocoptes musculinus.Journal of the American Association for Laboratory Animal Science : JAALAS · 2013
    Trial
  2. Article
  3. Article
  4. PCR and RT-PCR in the Diagnosis of Laboratory Animal Infections and in Health Monitoring.Journal of the American Association for Laboratory Animal Science : JAALAS · 2020
    Article
  5. Article
  6. Article
  7. Comparison of Diagnostic Methods and Sampling Sites for the Detection of Demodex musculi.Journal of the American Association for Laboratory Animal Science : JAALAS · 2018
    Article
  8. Combined evaluation of commonly used techniques, including PCR, for diagnosis of mouse fur mites.Journal of the American Association for Laboratory Animal Science : JAALAS · 2014
    Article
  9. Evaluation of diagnostic methods for Myocoptes musculinus according to age and treatment status of mice (Mus musculus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Erica E WeissCenter for Laboratory Animal Science, School of Veterinary Medicine, University of California, Davis, California, USA. eeweiss@ucdavis.edu
Kristin D Evans
Stephen M Griffey
University of California, Davis · US

Funding

UCD Mutant Mouse Regional Resource CenterU42OD012210 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2012 to 2026
$29.2M
Mouse Metabolic Phenotyping Center (MMPC) at UC DavisU24DK092993 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2011 to 2015
$4.1M
NIDDK NIH HHS U24 DK092993NIH HHS U42 OD012210
6 · The paper itself

Abstract

Fur mites were diagnosed in a colony of mice at our research institution. In the current study, we compared the effectiveness of PCR and tape test in a small population of mice at the onset of diagnosis and throughout treatment. Samples were collected 1 d prior to treatment with permethrin impregnated cotton balls and 6 and 12 wk after treatment. PCR confirmed the presence of Myocoptes musculinus and Radfordia affinis or Myobia musculi, but tape test confirmed only the presence of Myocoptes spp. The results of the PCR and tape test agreed 97.2% of the time during active infection on day 1, but only 59.5% and 48.4% of results coincided at 6 and 12 wk after treatment, respectively. At 6 wk, 11 of the 37 samples were PCR-negative but tape-test-positive, compared with 9 of the 31 samples at 12 wk. Our results show that PCR is a reliable diagnostic method during active fur mite infection but that false-negative results are possible after treatment. Negative PCR results after treatment should be interpreted carefully, and a secondary diagnostic method should be considered.

Indexed as

AcaricidesAnimalsFalse Negative ReactionsFemaleHairMaleMiceMice, Inbred C57BLMice, Inbred ICRMite InfestationsMitesPermethrinPolymerase Chain ReactionRodent DiseasesSensitivity and SpecificityAcaricidesPermethrin

Identifiers

PMID23312085
PMCPMC3447445
OpenAlexW1481401211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.