Evidence map›Paper›PMID 23308216›Full record

Trial reportPloS one2013

Missed opportunities: refusal to confirm reactive rapid HIV tests in the emergency department.

Ishani Ganguli, Jamie E Collins, William M Reichmann, Elena Losina, Jeffrey N Katz, Christian Arbelaez, Laurel A Donnell-Fink, Rochelle P Walensky

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00502944 nacompletednot on this map

Optimizing Strategies for Universal HIV Testing (The USHER Trial)

TypeinterventionalSponsorMassachusetts General HospitalRan2007 to 2008Enrolled4,855ConditionsHIV InfectionsArmsCounselor-based HIV screening, Emergency staff member-based HIV screening
NCT01258582 nacompletednot on this map

Optimizing Strategies for Universal HIV Testing (The USHER Trial): Phase II

TypeinterventionalSponsorMassachusetts General HospitalRan2009 to 2010Enrolled1,651ConditionsHIV InfectionsArmsOral HIV screening, Fingerstick HIV screening
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ishani GanguliDepartment of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Jamie E Collins
William M Reichmann
Elena Losina
Jeffrey N Katz
Christian Arbelaez
Laurel A Donnell-Fink
Rochelle P Walensky

Funding

Optimizing strategies for universal HIV testingR01MH073445 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI WALENSKY, ROCHELLE P. · 2006 to 2010
$3.3M
NIMH NIH HHS R01 MH073445
6 · The paper itself

Abstract

backgroundHIV infection remains a major US public health concern. While HIV-infected individuals now benefit from earlier diagnosis and improved treatment options, progress is tempered by large numbers of newly diagnosed patients who are lost to follow-up prior to disease confirmation and linkage to care. METHODOLOGY: In the randomized, controlled USHER trial, we offered rapid HIV tests to patients presenting to a Boston, MA emergency department. Separate written informed consent was required for confirmatory testing. In a secondary analysis, we compared participants with reactive results who did and did not complete confirmatory testing to identify factors associated with refusal to complete the confirmation protocol. PRINCIPAL

findingsThirteen of 62 (21.0%, 95% CI (11.7%, 33.2%)) participants with reactive rapid HIV tests refused confirmation; women, younger participants, African Americans, and those with fewer HIV risks, with lower income, and without primary care doctors were more likely to refuse. We projected that up to four true HIV cases were lost at the confirmation stage.

conclusionsThese findings underscore the need to better understand the factors associated with refusal to confirm reactive HIV testing and to identify interventions that will facilitate confirmatory testing and linkage to care among these populations.

trial registrationClinicalTrials.gov NCT00502944; NCT01258582.

Indexed as

HIVAdolescentAdultAgedAge FactorsAIDS SerodiagnosisBlack or African AmericanBostonEducational StatusEmergency Service, HospitalFemaleFluorescent Antibody TechniqueHispanic or LatinoHIV InfectionsHIV SeropositivityHumans

Identifiers

PMID23308216
PMCPMC3540076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.