Evidence map›Paper›PMID 23307984›Full record

GuidelineJournal of the National Comprehensive Cancer Network : JNCCN2013

Small cell lung cancer.

Gregory P Kalemkerian, Wallace Akerley, Paul Bogner, Hossein Borghaei, Laura Qm Chow, Robert J Downey, Leena Gandhi, Apar Kishor P Ganti, Ramaswamy Govindan, John C Grecula and 17 more

Abstract readPractice Guideline
In one paragraph

Guideline in Journal of the National Comprehensive Cancer Network : JNCCN, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 223 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
223citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

223 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
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  8. Trial
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  11. Effect of Whole-Brain and Intensity-Modulated Radiotherapy on Serum Levels of miR-21 and Prognosis for Lung Cancer Metastatic to the Brain.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Trial
  12. Trial
  13. Article
  14. Article
  15. Article
  16. Review
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  19. Review
  20. Treatment patterns and survival outcomes in patients with small-cell lung cancer following failure of first-line platinum-based chemotherapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article

163 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Gregory P Kalemkerian
Wallace Akerley
Paul Bogner
Hossein Borghaei
Laura Qm Chow
Robert J Downey
Leena Gandhi
Apar Kishor P Ganti
Ramaswamy Govindan
John C Grecula
James Hayman
Rebecca Suk Heist
Leora Horn
Thierry Jahan
Marianna Koczywas
Billy W Loo
Robert E Merritt
Cesar A Moran
Harvey B Niell
Janis O'Malley
Jyoti D Patel
Neal Ready
Charles M Rudin
Charles C Williams
Kristina Gregory
Miranda Hughes
National Comprehensive Cancer Network

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI WILLIAM George NELSON · 1985 to 2026
$208.6M
NCI NIH HHS P30 CA006973
6 · The paper itself

Abstract

Neuroendocrine tumors account for approximately 20% of lung cancers; most (≈15%) are small cell lung cancer (SCLC). These NCCN Clinical Practice Guidelines in Oncology for SCLC focus on extensive-stage SCLC because it occurs more frequently than limited-stage disease. SCLC is highly sensitive to initial therapy; however, most patients eventually die of recurrent disease. In patients with extensive-stage disease, chemotherapy alone can palliate symptoms and prolong survival in most patients; however, long-term survival is rare. Most cases of SCLC are attributable to cigarette smoking; therefore, smoking cessation should be strongly promoted.

Indexed as

Antineoplastic AgentsBrain NeoplasmsHumansLung NeoplasmsNeoplasm StagingRadiotherapySmall Cell Lung CarcinomaAntineoplastic Agents

Identifiers

PMID23307984
PMCPMC3715060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.