ReviewAngewandte Chemie (International ed. in English)2013
Highly fluorescent semiconducting polymer dots for biology and medicine.
Review in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
186 citing papers in PubMed.
- Composite and Blends of PFD and MEH-PPV Conjugated Polymer Nanoparticles: Combined Optical Properties and Quantum Yield Increase by FRET.ACS omega · 2026Article
- Advances in Boron-Doped Carbon Dots: Computational Understanding on its Structural Modification and Multifunctional Applications.ACS omega · 2026Review
- Creating Semiconducting Polymer Dots with Enhanced Performance Through a Simple Mixed Antisolvent Approach.Biosensors · 2026Article
- Polymer Nanoparticles in Medical Applications-Future Directions.Nanomaterials (Basel, Switzerland) · 2026Review
- Conjugated Polymeric Nanostructures as Potential Tools in DNA Nanotechnology: Interactions with the Double Helix.ACS omega · 2026Article
- Hydrogel-Based Semiconductors: Principles, Types, and Emerging Applications.Gels (Basel, Switzerland) · 2026Review
- Magnetic borylated conjugated polymer nanoparticles for deep-red optical and lifetime imaging.Journal of materials chemistry. B · 2026Article
- Rational Design of New Biocompatible Near-Infrared Conjugated Polymer Nanoparticles for Biomedical Applications.Macromolecules · 2026Article
- Donor-Acceptor-Donor Small-Molecular Dots are Brighter than Polymer Dots of Similar Chromophore Units.ACS applied materials & interfaces · 2025Article
- Designing Physical Unclonable Functions From Optically Active Materials.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Precision Chemistry in Precision Diagnostics.Precision chemistry · 2025Article
- Toward Organic Mimics of Metallic Nanoparticles: Tuning and Enhancing Fluorescence in Binary Dye-Based Nanoparticles.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Inter-Nanoparticle FRET for Biosensing: Photophysics Versus Size.Angewandte Chemie (International ed. in English) · 2025Review
- Article
- Advances and Innovations in Conjugated Polymer Fluorescent Sensors for Environmental and Biological Detection.Biosensors · 2025Review
- Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging.Advanced healthcare materials · 2025Review
- Spectral Flow Cytometry: The Current State and Future of the Technology.International journal of molecular sciences · 2025Review
- POSA for fast, amplified and multiplexed protein imaging.Nature communications · 2025Article
- Multi-functional near-infrared fluorescent polymer dot-siRNA for gene expression regulation.Journal of materials chemistry. B · 2025Article
- Bright and stable anti-counterfeiting devices with independent stochastic processes covering multiple length scales.Nature communications · 2025Article
126 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
In recent years, semiconducting polymer nanoparticles have attracted considerable attention because of their outstanding characteristics as fluorescent probes. These nanoparticles, which primarily consist of π-conjugated polymers and are called polymer dots (Pdots) when they exhibit small particle size and high brightness, have demonstrated utility in a wide range of applications such as fluorescence imaging and biosensing. In this review, we summarize recent findings of the photophysical properties of Pdots which speak to the merits of these entities as fluorescent labels. This review also highlights the surface functionalization and biomolecular conjugation of Pdots, and their applications in cellular labeling, in vivo imaging, single-particle tracking, biosensing, and drug delivery. We discuss the relationship between the physical properties and performance, and evaluate the merits and limitations of the Pdot probes for certain imaging tasks and fluorescence assays. We also tackle the current challenges of Pdots and share our perspective on the future directions of the field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.