ArticleOral and maxillofacial surgery2014
Impact of the use of plasma rich in growth factors (PRGF) on the quality of life of patients treated with endodontic surgery when a perforation of sinus membrane occurred. A comparative study.
Article in Oral and maxillofacial surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Impact of regenerative procedure on the healing process following surgical root canal treatment: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Efficacy of plasma rich in growth factor used for dry socket management: a systematic review.Medicina oral, patologia oral y cirugia bucal · 2019Pooled it
- Root-end surgery with leucocyte- and platelet-rich fibrin and an occlusive membrane: a randomized controlled clinical trial on patients' quality of life.Clinical oral investigations · 2018Trial
- Optimising Outcomes in Endodontic Microsurgery: Evidence, Uncertainties and Future Directions.International endodontic journal · 2026Review
- Effect of piezoelectric device on intraoperative hemostasis and quality of life after endodontic microsurgery in maxillary molars: A randomized controlled trial.Journal of conservative dentistry and endodontics · 2026Article
- How to explain the beneficial effects of leukocyte- and platelet-rich fibrin.Periodontology 2000 · 2025Review
- The Effectiveness of Autologous Platelet Concentrates in the Clinical and Radiographic Healing after Endodontic Surgery: A Systematic Review.Materials (Basel, Switzerland) · 2023Review
- PROMs Following Root Canal Treatment and Surgical Endodontic Treatment.International dental journal · 2023Review
- One-year implant survival following lateral window sinus augmentation using plasma rich in growth factors (PRGF): a retrospective study.Medicina oral, patologia oral y cirugia bucal · 2020Article
- Immediate post-extraction implants with or without pure platelet-rich plasma: a 5-year follow-up study.Oral and maxillofacial surgery · 2017Article
- Microsurgical re-treatment of an endodontically treated tooth with an apically located incomplete vertical root fracture: a clinical case report.Restorative dentistry & endodontics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of this retrospective investigation was to evaluate the postoperative quality of life after endodontic surgery in maxillary molars when a sinus membrane perforation occurred and platelet concentrates were used. MATERIALS AND
methodsIncluded patients were treated by microsurgical endodontic treatment in molar and premolar maxillary regions between 2007 and 2010. Patients who fulfilled the inclusion criteria were screened. Data from the quality of life questionnaire were analyzed. The use of plasma rich in growth factors (PRGF) (test group) was compared with a control group when a Schneiderian membrane perforation occurred during endodontic surgery performed with a modern technique in maxillary molars and premolars.
resultsA total of 20 patients (12 in the control group and eight in the test group) fulfilled the inclusion criteria. No differences were evaluated at baseline for clinical parameters. Significantly improved patients' quality of life was observed in the test group considering symptoms as swelling, bad breath or taste, and pain. Functional activities were less impaired in the test group and swelling was significantly higher in the control group. In the test group, pain was significantly lower than the control group during the first 6 days after surgery and also, the consumption of painkillers was lower for patients belonging to the test group even if it was not statistically significant. DISCUSSION: In general, a small sinus membrane perforation (less than 6 mm) during endodontic surgery did not cause severe complications. The use of platelet concentrates could be effective in reducing the impact on patients' quality of life, decreasing pain and surgery side effects as well as swelling.
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