SynthesisDigestive diseases and sciences2013
Endoscopic ultrasound elastography for differential diagnosis of pancreatic masses: a meta-analysis.
Synthesis in Digestive diseases and sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The efficiency of contrast-enhanced endoscopic ultrasound (EUS) combined with EUS elastography for pancreatic cancer diagnosis: a systematic review and meta-analysis.Ultrasonography (Seoul, Korea) · 2023Pooled it
- Endo-hepatology: Bridging the gap between lumen and liver.World journal of gastroenterology · 2025Review
- Endoscopic Ultrasound (EUS) Guided Elastography.Diagnostics (Basel, Switzerland) · 2023Review
- Review
- The potential of endoscopic ultrasound sonography (EUS)-elastography in determining the stage of pancreatic tumor.Gastroenterology and hepatology from bed to bench · 2021Article
- Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA) with Image Enhancement.Diagnostics (Basel, Switzerland) · 2020Review
- Endoscopic ultrasound (EUS) and the management of pancreatic cancer.BMJ open gastroenterology · 2020Review
- Endoscopic ultrasonography in pancreatic diseases: advances in tissue acquisition.Endoscopy international open · 2019Review
- Impact of endoscopic ultrasonography on diagnosis of pancreatic cancer.Journal of gastroenterology · 2019Review
- Technique of qualitative and semiquantitative EUS elastography in pancreatic examination.Endoscopic ultrasound · 2017Article
- Endoscopic ultrasound in diagnosis of solid pancreatic lesions: Elastography or contrast-enhanced harmonic alone versus the combination.Endoscopy international open · 2017Article
- Maximizing the endosonography: The role of contrast harmonics, elastography and confocal endomicroscopy.World journal of gastroenterology · 2017Review
- The Role of Real Time Endoscopic Ultrasound Guided Elastography for Targeting EUS-FNA of Suspicious Pancreatic Masses: A Review of the Literature and A Single Center Experience.JOP : Journal of the pancreas · 2016Article
- Endoscopic ultrasound elastography: Current status and future perspectives.World journal of gastroenterology · 2015Review
- Applications of endoscopic ultrasound in pancreatic cancer.World journal of gastroenterology · 2014Review
- Can elastography replace fine needle aspiration?Endoscopic ultrasound · 2014Review
- Accuracy of visual scoring and semi-quantification of ultrasound strain elastography--a phantom study.PloS one · 2014Article
- Diagnostic evaluation of solid pancreatic masses.Current gastroenterology reports · 2013Review
- Endoscopic ultrasound elastography for pancreatic cancer diagnosis: a step forward?Clinical endoscopy · 2013Article
- Application of artificial intelligence for diagnosis of pancreatic ductal adenocarcinoma by EUS: A systematic review and meta-analysis.Endoscopic ultrasoundReview
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDistinguishing malignant from benign pancreatic tumors is challenging with current imaging techniques. Endoscopic ultrasound (EUS) elastography has further improved the efficacy of EUS for characterizing pancreatic lesions.
aimsTo assess, by combining data from existing trials, the accuracy of EUS elastography in diagnosing malignant tumors for patients with pancreatic masses.
methodsAll relevant studies published were identified by systematic searching of databases. A meta-analysis was performed using a random-effects model to combine study results.
resultsSeven studies involving 752 patients were included. The sensitivity of EUS elastography for differential diagnosis of solid pancreatic masses was 97 % (95 % CI, 0.95-0.98), and the specificity was 76 % (95 % CI, 0.69-0.82). The area under the curve under summary receiver operating characteristic (SROC) was 0.9529. The combined positive likelihood ratio was 3.71 (95 % CI, 2.72-5.07), and the negative likelihood ratio was 0.05 (95 % CI, 0.02-0.13).
conclusionOur meta-analysis shows that EUS elastography is a useful tool for differential diagnosis of solid pancreatic neoplasms with very high sensitivity and relatively low specificity. The results indicate that EUS elastography not only provides information complementary to that from EUS but also potentially increases the yield of fine needle aspiration and reduces the number of unnecessary biopsies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.