Evidence map›Paper›PMID 23306189›Full record

ReviewNutrients2013

Role of endogenous microbiota, probiotics and their biological products in human health.

Gordon S Howarth, Hanru Wang

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
23.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 141 citations in OpenAlex.

  1. Trial
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  7. Agro-ecosystem of honeybees as source for native probiotic yeasts.World journal of microbiology & biotechnology · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
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  16. Treatment with the Probiotic Product AviguardInternational journal of molecular sciences · 2021
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gordon S HowarthSchool of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy Campus, South Australia 5371, Australia. gordon.howarth@adelaide.edu.au
Hanru Wang
University of Adelaide · AUWomen's and Children's Health Network · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although gut diseases such as inflammatory bowel disease, mucositis and the alimentary cancers share similar pathogenetic features, further investigation is required into new treatment modalities. An imbalance in the gut microbiota, breached gut integrity, bacterial invasion, increased cell apoptosis to proliferation ratio, inflammation and impaired immunity may all contribute to their pathogenesis. Probiotics are defined as live bacteria, which when administered in sufficient amounts, exert beneficial effects to the gastrointestinal tract. More recently, probiotic-derived factors including proteins and other molecules released from living probiotics, have also been shown to exert beneficial properties. In this review we address the potential for probiotics, with an emphasis on probiotic-derived factors, to reduce the severity of digestive diseases and further discuss the known mechanisms by which probiotics and probiotic-derived factors exert their physiological effects.

Indexed as

AnimalsBiological ProductsGastrointestinal DiseasesGastrointestinal TractHumansInflammatory Bowel DiseasesIntestinal MucosaIntestinesMetagenomeProbioticsBiological Products

Identifiers

PMID23306189
PMCPMC3571638
OpenAlexW2164525467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.