Evidence map›Paper›PMID 23305775›Full record

ArticleDiagnostic microbiology and infectious disease2013

Perspectives and concerns regarding antimicrobial agent shortages among infectious disease specialists.

Adi V Gundlapalli, Susan E Beekmann, Donald R Graham, Philip M Polgreen, Infectious Diseases Society of America's Emerging Infections Network

Abstract read
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
23.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
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  12. Trends in Pricing and Generic Competition Within the Oral Antibiotic Drug Market in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. The Infectious Diseases Society of America emerging infections network: bridging the gap between clinical infectious diseases and public health.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014
    Article
  19. Why drug shortages are an ethical issue.The Australasian medical journal · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Adi V GundlapalliUniversity of Utah School of Medicine, Salt Lake City, UT 84132, USA. adi.gundlapalli@hsc.utah.edu
Susan E Beekmann
Donald R Graham
Philip M Polgreen
Infectious Diseases Society of America's Emerging Infections Network
University of Iowa · USSpringfield Clinic · USUniversity of Utah · US

Funding

Vascular stabilization as a broad theraprutic platform for biodefenseU54AI065357 · NIAID · COLORADO STATE UNIVERSITY-FORT COLLINS · PI SCHWEIZER, HERBERT P. · 2005 to 2013
$77.5M
NIAID NIH HHS U54 AI065357PHITPO CDC HHS 5P01HK000069PHITPO CDC HHS P01 HK000069PHS HHS 1 U54 A1065357PHS HHS U50 CCU112346
6 · The paper itself

Abstract

Antimicrobial shortages have made treating certain infections more difficult. A web-based survey asking about experience with antimicrobial drug shortages was distributed in 2011 to 1328 infectious diseases physician members of the Emerging Infectious Diseases Network of the Infectious Diseases Society of America. A majority (78%) of 627 respondents reported needing to modify antimicrobial choices because of drug shortages within the past 2 years. Antimicrobials most often reported as not available or available but in short supply were trimethoprim-sulfamethoxazole injection (by 65% of respondents), amikacin (by 58%), aztreonam (by 31%), and foscarnet (by 22%). Most respondents (55%) reporting a shortage indicated that the shortage adversely affected patient outcomes and that they were forced to use alternative and second line agents which were either less effective, more toxic, or more costly. Most (70%) indicated that they learned about the shortage from contact with the pharmacy after trying to prescribe a drug in short supply. More effective means of informing physicians about drug shortages is critical to lessen the impact on patient care.

Indexed as

AmikacinAnti-Infective AgentsAztreonamCommunicable DiseasesDelivery of Health CareDrug SubstitutionFoscarnetHealth Care SurveysHumansPharmacy Service, HospitalPhysiciansSocieties, MedicalTrimethoprim, Sulfamethoxazole Drug CombinationAmikacinAnti-Infective AgentsAztreonamFoscarnetTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID23305775
PMCPMC5815827
OpenAlexW2167341868

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.