ReviewCurrent protein & peptide science2012
Protein-carbohydrate interactions studied by NMR: from molecular recognition to drug design.
Review in Current protein & peptide science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Serotonergic Signaling Rewired: A Lipid Raft-Controlled Model of Synaptic Transmission Grounded in the Fundamental Parameters of Biological Systems.Life (Basel, Switzerland) · 2026Article
- Utilization of Fish Byproduct in Edible Films: A Sustainable Approach to Improving Fillet Shelf Life.Food science & nutrition · 2025Article
- The energetic landscape of CH-π interactions in protein-carbohydrate binding.Chemical science · 2025Article
- Effect of legume proteins on the structure and digestibility of wheat starch-lauric acid complexes.Food chemistry: X · 2024Article
- Article
- Imaging Saturation Transfer Difference (STD) NMR: Affinity and Specificity of Protein-Ligand Interactions from a Single NMR Sample.Journal of the American Chemical Society · 2023Article
- Structure-Based Neural Network Protein-Carbohydrate Interaction Predictions at the Residue Level.bioRxiv : the preprint server for biology · 2023Article
- Article
- Structure-based neural network protein-carbohydrate interaction predictions at the residue level.Frontiers in bioinformatics · 2023Article
- Design of ionic liquids containing glucose and choline as drug carriers, finding the link between QM and MD studies.Scientific reports · 2022Article
- Carbohydrate-based drugs launched during 2000Acta pharmaceutica Sinica. B · 2022Review
- Investigation of the Binding of Lectins with Polymer Glycoconjugates and the Glycoconjugates Containing Silver Nanoparticles by Means of Optical Spectroscopy and Light Scattering.Polymer science. Series A, Chemistry, physics · 2022Article
- Preparation of Natural Food-Grade Core-Shell Starch/Zein Microparticles by Antisolvent Exchange and Transglutaminase Crosslinking for Reduced Digestion of Starch.Frontiers in nutrition · 2022Article
- A Simple Biomimetic Receptor Selectively Recognizing the GlcNAcAngewandte Chemie (International ed. in English) · 2021Article
- Differential effects of putative N-glycosylation sites in human Tau on Alzheimer's disease-related neurodegeneration.Cellular and molecular life sciences : CMLS · 2021Article
- Carbohydrate-Protein Interactions: Advances and Challenges.Communications in information and systems · 2021Article
- Effects of Stereochemistry and Hydrogen Bonding on Glycopolymer-Amyloid-β Interactions.Biomacromolecules · 2020Article
- Biochemical determinants of the IGFBP-3-hyaluronan interaction.FEBS open bio · 2020Article
- Rational identification and characterisation of peptide ligands for targeting polysialic acid.Scientific reports · 2020Article
- Comparative Study of ArylMolecules (Basel, Switzerland) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diseases that result from infection are, in general, a consequence of specific interactions between a pathogenic organism and the cells. The study of host-pathogen interactions has provided insights for the design of drugs with therapeutic properties. One area that has proved to be promising for such studies is the constituted by carbohydrates which participate in biological processes of paramount importance. On the one hand, carbohydrates have shown to be information carriers with similar, if not higher, importance than traditionally considered carriers as amino acids and nucleic acids. On the other hand, the knowledge on molecular recognition of sugars by lectins and other carbohydrate-binding proteins has been employed for the development of new biomedical strategies. Biophysical techniques such as X-Ray crystallography and NMR spectroscopy lead currently the investigation on this field. In this review, a description of traditional and novel NMR methodologies employed in the study of sugar-protein interactions is briefly presented in combination with a palette of NMR-based studies related to biologically and/or pharmaceutically relevant applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.