ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2012
Ontological approach for safe and effective polypharmacy prescription.
Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Using clinical reasoning ontologies to make smarter clinical decision support systems: a systematic review and data synthesis.Journal of the American Medical Informatics Association : JAMIA · 2020Pooled it
- Ontologies Applied in Clinical Decision Support System Rules: Systematic Review.JMIR medical informatics · 2023Review
- Polypharmacy and precision medicine.Cambridge prisms. Precision medicine · 2023Review
- Pharmaceutical Side Effects and Mental Health Paradoxes among Racial-Ethnic Minorities.Journal of health and social behavior · 2020Article
- Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies.BMC medical informatics and decision making · 2015Article
- Adoption of clinical decision support in multimorbidity: a systematic review.JMIR medical informatics · 2015Review
- Ontological approach to reduce complexity in polypharmacy.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intake of multiple medications in patients with various medical conditions challenges the delivery of medical care. Initial empirical studies and pilot implementations seem to indicate that generic safe and effective multi-drug prescription principles could be defined and reused to reduce adverse drug events and to support compliance with medical guidelines and drug formularies. Given that ontologies are known to provide well-principled, sharable, setting-independent and machine-interpretable declarative specification frameworks for modeling and reasoning on biomedical problems, we explore here their use in the context of multi-drug prescription. We propose an ontology for modeling drug-related knowledge and a repository of safe and effective generic prescription principles. To test the usability and the level of granularity of the developed ontology-based specification models and heuristic we implemented a tool that computes the complexity of multi-drug treatments, and a decision aid to check the safeness and effectiveness of prescribed multi-drug treatments.
Indexed as
Identifiers
23304299PMC3540569What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.