Evidence map›Paper›PMID 23303500›Full record

ArticleJournal of clinical microbiology2013

A real-time PCR assay for rapid detection and quantification of Exserohilum rostratum, a causative pathogen of fungal meningitis associated with injection of contaminated methylprednisolone.

Yanan Zhao, Ruta Petraitiene, Thomas J Walsh, David S Perlin

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 35 citations in OpenAlex.

  1. A Repertoire of Clinical Non-Dermatophytes Moulds.Journal of fungi (Basel, Switzerland) · 2023
    Review
  2. Article
  3. Article
  4. Black Molds and Melanized Yeasts Pathogenic to Humans.Cold Spring Harbor perspectives in medicine · 2014
    Review
  5. Article
  6. Mold infections of the central nervous system.The New England journal of medicine · 2014
    Review
  7. Containing infectious disease.Pathogens and disease · 2014
    Article
  8. Article
  9. Iatrogenic fungal infections of central nervous system.Current neurology and neuroscience reports · 2013
    Review
  10. Article
  11. What can we learn and what do we need to know amidst the iatrogenic outbreak of Exserohilum rostratum meningitis?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yanan ZhaoPublic Health Research Institute Center, UMDNJ-NJMS, Newark, New Jersey, USA.
Ruta Petraitiene
Thomas J Walsh
David S Perlin
Cornell University · USRutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A species-specific molecular beacon real-time PCR assay was developed for rapid diagnosis of Exserohilum rostratum infection. As low as 100 fg of E. rostratum DNA can be reliably detected in the presence of 50 ng of human DNA, with a dynamic linear quantification range from 20 ng to 200 fg.

Indexed as

Drug ContaminationAscomycotaColony Count, MicrobialHumansInjectionsMeningitis, FungalMethylprednisoloneReal-Time Polymerase Chain ReactionSensitivity and SpecificityMethylprednisolone

Identifiers

PMID23303500
PMCPMC3592047
OpenAlexW1997513470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.