Evidence map›Paper›PMID 23301778›Full record

ReviewAnalytical chemistry2013

Integral membrane proteins and bilayer proteomics.

Julian P Whitelegge

Open access · greenAbstract readReview
In one paragraph

Review in Analytical chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 93 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Top-Down Identification and Sequence Analysis of Small Membrane Proteins Using MALDI-MS/MS.Journal of the American Society for Mass Spectrometry · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Novel Strategies to Address the Challenges in Top-Down Proteomics.Journal of the American Society for Mass Spectrometry · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Julian P WhiteleggeThe Pasarow Mass Spectrometry Laboratory, The NPI-Semel Institute for Neuroscience and Human Behavior, The David Geffen School of Medicine, University of California, Los Angeles, 760 Westwood Plaza, Los Angeles, California 90095, United States. jpw@chem.ucla.edu
University of California, Los Angeles · US

Funding

High Resolution Hybrid FT-ICR Mass SpectrometerS10RR023045 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LOO, JOSEPH A · 2006 to 2006
$1.2M
Improving Rate/Quality Limitations in Membrane Protein Structure DeterminationP50GM088499 · NIGMS · PURDUE UNIVERSITY · PI CRAMER, WILLIAM A. · 2009 to 2010
$1.0M
NCRR NIH HHS S10 RR023045NIGMS NIH HHS GM088499NIGMS NIH HHS P50 GM088499
6 · The paper itself

Abstract

Integral membrane proteins reside within the bilayer membranes that surround cells and organelles, playing critical roles in movement of molecules across them and the transduction of energy and signals. While their extreme amphipathicity presents technical challenges, biological mass spectrometry has been applied to all aspects of membrane protein chemistry and biology, including analysis of primary, secondary, tertiary, and quaternary structures as well as the dynamics that accompany functional cycles and catalysis.

Indexed as

Amino Acid SequenceAnimalsCell MembraneLipid BilayersMass SpectrometryMembrane ProteinsMolecular Sequence DataProtein Processing, Post-TranslationalProteomicsLipid BilayersMembrane Proteins

Identifiers

PMID23301778
PMCPMC3664232
OpenAlexW2056606518

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.