ArticlePloS one2012
Amino acid- vs. peptide-odorants: responses of individual olfactory receptor neurons in an aquatic species.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Olfactory cues elicit species-specific locomotive responses in poison frog tadpoles.microPublication biology · 2025Article
- Behavioral Variables to Assess the Toxicity of Unionized Ammonia in Aquatic Snails: Integrating Movement and Feeding Parameters.Archives of environmental contamination and toxicology · 2022Article
- Electrophysiological responses to conspecific odorants in Xenopus laevis show potential for chemical signaling.PloS one · 2022Article
- Microbial metabolism mediates interactions between dissolved organic matter and clay minerals in streamwater.Scientific reports · 2016Article
- Different expression domains for two closely related amphibian TAARs generate a bimodal distribution similar to neuronal responses to amine odors.Scientific reports · 2015Article
- Mechanisms underlying odorant-induced and spontaneous calcium signals in olfactory receptor neurons of spiny lobsters, Panulirus argus.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amino acids are widely used waterborne olfactory stimuli proposed to serve as cues in the search for food. In natural waters the main source of amino acids is the decomposition of proteins. But this process also produces a variety of small peptides as intermediate cleavage products. In the present study we tested whether amino acids actually are the natural and adequate stimuli for the olfactory receptors they bind to. Alternatively, these olfactory receptors could be peptide receptors which also bind amino acids though at lower affinity. Employing calcium imaging in acute slices of the main olfactory epithelium of the fully aquatic larvae of Xenopus laevis we show that amino acids, and not peptides, are more effective waterborne odorants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.