ArticlePlant physiology2013
The MPK6-ERF6-ROS-responsive cis-acting Element7/GCC box complex modulates oxidative gene transcription and the oxidative response in Arabidopsis.
Article in Plant physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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67 citing papers in PubMed, 171 citations in OpenAlex.
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- Unraveling key genes and pathways involved in Verticillium wilt resistance by integrative GWAS and transcriptomic approaches in Upland cotton.Functional & integrative genomics · 2025Article
- Perception and processing of stress signals by plant mitochondria.The Plant journal : for cell and molecular biology · 2024Review
- Multi-omics analysis revealed the mechanism underlying flavonol biosynthesis during petal color formation in Camellia Nitidissima.BMC plant biology · 2024Article
- MAPK Cascades in Plant Microbiota Structure and Functioning.Journal of microbiology (Seoul, Korea) · 2024Review
- Plant disease resistance outputs regulated by AP2/ERF transcription factor family.Stress biology · 2024Review
- The transcription factor FcMYB3 responds toFrontiers in plant science · 2024Article
- Identification of a putative kinase interacting domain in the durum wheat catalase 1 (TdCAT1) protein.Heliyon · 2023Article
- Modulation of the Berry Skin Transcriptome of cv. Tempranillo Induced by Water Stress Levels.Plants (Basel, Switzerland) · 2023Article
- An miR156-regulated nucleobase-ascorbate transporter 2 confers cadmium tolerance via enhanced anti-oxidative capacity in barley.Journal of advanced research · 2023Article
- MicroRNA candidate miRcand137 in apple is induced by Botryosphaeria dothidea for impairing host defense.Plant physiology · 2022Article
- Role of cassava CC-type glutaredoxin MeGRXC3 in regulating sensitivity to mannitol-induced osmotic stress dependent on its nuclear activity.BMC plant biology · 2022Article
- Reactive oxygen species-related genes participate in resistance to cucumber green mottle mosaic virus infection regulated by boron inFrontiers in plant science · 2022Article
- The transcription factor ORA59 exhibits dual DNA binding specificity that differentially regulates ethylene- and jasmonic acid-induced genes in plant immunity.Plant physiology · 2021Article
- Response of Wheat DREB Transcription Factor to Osmotic Stress Based on DNA Methylation.International journal of molecular sciences · 2021Article
- TGA class II transcription factors are essential to restrict oxidative stress in response to UV-B stress in Arabidopsis.Journal of experimental botany · 2021Article
- Plant Mitogen-Activated Protein Kinase Cascades in Environmental Stresses.International journal of molecular sciences · 2021Review
7 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reactive oxygen species (ROS) have been characterized as both important signaling molecules and universal stressors that mediate many developmental and physiological responses. So far, details of the transcriptional mechanism of ROS-responsive genes are largely unknown. In the study reported here, we identified seven potential ROS-responsive cis-acting elements (ROSEs) from the promoters of genes up-regulated by ROS in Arabidopsis (Arabidopsis thaliana). We also found that the APETALA2/ethylene-responsive element binding factor6 (ERF6) could bind specifically to the ROSE7/GCC box. Coexpression of ERF6 enhanced luciferase activity driven by ROSE7. The deficient mutants of ERF6 showed growth retardation and higher sensitivity to photodamage. ERF6 interacted physically with mitogen-activated protein kinase6 (MPK6) and also served as a substrate of MPK6. MPK6-mediated ERF6 phosphorylation at both serine-266 and serine-269 affected the dynamic alternation of the ERF6 protein, which resulted in changes in ROS-responsive gene transcription. These data might provide new insight into the mechanisms that regulate ROS-responsive gene transcription via a complex of MPK6, ERF6, and the ROSE7/GCC box under oxidative stress or a fluctuating light environment.
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