Evidence map›Paper›PMID 23299876›Full record

ArticleAIDS and behavior2013

Sleep, function and HIV: a multi-method assessment.

Charlene E Gamaldo, Adam P Spira, Rebecca S Hock, Rachel E Salas, Justin C McArthur, Paula M David, Gilbert Mbeo, Michael T Smith

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Sleep, Prospective Memory, and Immune Status among People Living with HIV.International journal of environmental research and public health · 2021
    Article
  13. Functional MRI Correlates of Sleep Quality in HIV.Nature and science of sleep · 2021
    Article
  14. Review
  15. Identifying Sleep Biomarkers to Evaluate Cognition in HIV.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Cognitive Trajectory Phenotypes in Human Immunodeficiency Virus-Infected Patients.Journal of acquired immune deficiency syndromes (1999) · 2019
    Article
  20. Biological clocks: their relevance to immune-allergic diseases.Clinical and molecular allergy : CMA · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Charlene E GamaldoDepartment of Neurology, The Johns Hopkins Outpatient Center, Johns Hopkins University, 600 N. Wolfe St., Meyer 6-119, Baltimore, MD, 21287, USA, cgamald1@jhmi.edu.
Adam P Spira
Rebecca S Hock
Rachel E Salas
Justin C McArthur
Paula M David
Gilbert Mbeo
Michael T Smith
Johns Hopkins University · US

Funding

Institute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8M
Therapeutic CoreP30MH075673 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Leah Helane Rubin, Barbara Stauch Slusher · 2006 to 2026
$33.2M
PSYCHIATRIC EPIDEMIOLOGY TRAINING PROGRAMT32MH014592 · NIMH · JOHNS HOPKINS UNIVERSITY · PI HEATHER E VOLK, Peter P. Zandi · 1985 to 2026
$8.5M
Translational Research in Neuro-AIDS and Mental HealthR25MH080661 · NIMH · JOHNS HOPKINS UNIVERSITY · PI MCARTHUR, JUSTIN CHARLES. · 2007 to 2019
$2.9M
Sleep Disturbances and Functional Decline in EldersK01AG033195 · NIA · JOHNS HOPKINS UNIVERSITY · PI SPIRA, ADAM PETER · 2009 to 2013
$645k
NCRR NIH HHS UL1 RR 025005NCRR NIH HHS UL1 RR025005NIA NIH HHS K01 AG033195NIMH NIH HHS 5P30MH075673-S02NIMH NIH HHS P30 MH075673NIMH NIH HHS R25 MH080661NIMH NIH HHS T32 MH014592
6 · The paper itself

Abstract

Amongst HIV+ individuals, sleep complaints have been recognized as common and debilitating; but have rarely been formally assessed or compared to controls using validated sleep tools. In this study we conducted structured interview for sleep disorders, polysomnography, 2-week home (ambulatory) monitoring and validated sleep/functional questionnaires. 56 % (14/25) of HIV+ participants and 0 % (0/19) of controls fulfilled the diagnostic criteria for insomnia. Insomnia severity scores were correlated with fatigue and anxiety symptoms. Sleep latency on 2-week actigraphy was significantly longer (P = 0.027) for HIV+ participants and associated with lower MOS-HIV scores. Sleep quality was significantly reduced in HIV+ participants based on validated questionnaires of overall sleep quality (P = 0.0017) and insomnia related symptoms (P < 0.001) even after adjusting for education and affective symptoms. HIV+ individuals are suffering with under-diagnosed sleep disorders that are negatively impacting quality of life and functional capabilities. Further studies aimed at improving recognition of sleep disorders and implementation of efficacious medical and behavioral treatment could improve functioning and disease management.

Indexed as

Activities of Daily LivingQuality of LifeActigraphyAnti-HIV AgentsAnxietyDrug Therapy, CombinationFatigueFemaleHIV InfectionsHumansMaleMiddle AgedMonitoring, AmbulatoryPolysomnographyPractice Guidelines as TopicProspective StudiesAnti-HIV Agents

Identifiers

PMID23299876
PMCPMC4341914
OpenAlexW2031350846

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.