Trial reportEuropean journal of clinical nutrition2013
Fruit and vegetable intake and the association with glucose parameters: a cross-sectional analysis of the Let's Prevent Diabetes Study.
Trial report in European journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 58 citations in OpenAlex.
- Trial
- Effects of Food Label Use on Diet Quality and Glycemic Control Among Latinos With Type 2 Diabetes in a Community Health Worker-Supported Intervention.American journal of public health · 2016Trial
- Group-based activities with on-site childcare and online support improve glucose tolerance in women within 5 years of gestational diabetes pregnancy.Cardiovascular diabetology · 2014Trial
- Dose-response effect of fruit and vegetables on insulin resistance in people at high risk of cardiovascular disease: a randomized controlled trial.Diabetes care · 2013Trial
- Healthcare provider perceptions of a pediatric fruit and vegetable prescription program: a qualitative study.BMC nutrition · 2026Article
- The Impacts of Global Climate Change and Environmental Security on Fruits and Vegetables-A Policy-Technology Nexus Perspective.Foods (Basel, Switzerland) · 2025Review
- Food and nutrition security of adolescents and young adults NEETs and non-NEETs in two low socioeconomic urban settlements in South Africa.BMC research notes · 2025Article
- A comparative study of fruit and vegetable consumption and its association with metabolic risk factors for non communicable diseases among rural and urban males in Zimbabwe.Frontiers in nutrition · 2025Article
- Associations of fruit intake with adiposity and cardiometabolic biomarkers in UK Biobank.BMC public health · 2024Article
- 'Nobody Shops at the Neighborhood Store': Leveraging a Community's Pediatric Fresh Produce Prescription Program to Inform Future Participating Store Redemption Locations.Cities & health · 2024Article
- Caregiver-reported barriers to engagement in a paediatric fresh fruit and vegetable prescription programme.Journal of nutritional science · 2024Article
- Association between adverse childhood experiences and fruit and vegetable intake among a national sample of U.S. adults.Preventive medicine reports · 2023Article
- Composite dietary antioxidant index was negatively associated with the prevalence of diabetes independent of cardiovascular diseases.Diabetology & metabolic syndrome · 2023Article
- Relationship Between Vitamins and Diabetes.Cureus · 2023Review
- The Association between Unhealthy Food Consumption and Impaired Glucose Metabolism among Adults with Overweight or Obesity: A Cross-Sectional Analysis of the Indonesian Population.Journal of obesity · 2023Article
- Fruit Intake and Changes of Cardio-Metabolic Risk Factors in People with Obesity.Korean journal of family medicine · 2021Article
- Low Plasma Ascorbate Levels in Type 2 Diabetic Patients With Adequate Dietary Vitamin C.Journal of laboratory physicians · 2021Article
- Glycemic Control Among People Living with Diabetes and Human Immunodeficiency Virus in Ethiopia: Leveraging Clinical Care for the Looming Co-Epidemics.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- The risk, perceived and actual, of developing type 2 diabetes mellitus for mothers of preschool children in urban China.PloS one · 2019Article
- The dietary acid load is higher in subjects with prediabetes who are at greater risk of diabetes: a case-control study.Diabetology & metabolic syndrome · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDietary recommendations for the prevention of type 2 diabetes mellitus include the message to consume 400 g fruit and vegetables per day. Measurement of habitual diet is inherently difficult, yet errors due to self-report can be eliminated by the use of nutritional biomarkers. The aim of this study was to determine plasma vitamin C concentrations as a biomarker for fruit and vegetable intake in individuals identified at high risk of diabetes. Fruit and vegetables may confer benefit via their antioxidant capacity, thus we also measured urinary F₂-isoprostanes as a marker for oxidative stress. SUBJECTS/
methodsParticipants recruited from a high-risk population as part of a diabetes prevention trial provided fasting blood samples and a spot urine sample for the quantification of plasma vitamin C and F₂-isoprostanes, respectively. We compared glycaemic parameters by the increments of the standard deviation of plasma vitamin C using multiple regression models.
resultsMean plasma vitamin C of participants was 39.3 μmol/l (s.d. 21.8). In the unadjusted model, 1 s.d. plasma vitamin C was significantly and inversely associated with HbA1c, fasting and 2 h blood glucose (P ≤ 0.0001). Relationships remained significant after adjustment for demographic variables and confounding factors. No significant association was observed between plasma vitamin C and urinary F₂-isoprostanes.
conclusionThe data adds to the evidence that small lifestyle changes may influence glucose regulation. The role that fruit and vegetables independently have should be investigated further.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.