ArticleThe Journal of surgical research2013
Do older Americans undergo stoma reversal following low anterior resection for rectal cancer?
Article in The Journal of surgical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- The application of defunctioning stomas after low anterior resection of rectal cancer.Surgery today · 2019Pooled it
- Does ghost ileostomy have a role in the laparoscopic rectal surgery era? A randomized controlled trial.Surgical endoscopy · 2015Trial
- Real-world outcomes following dehydrated human amnion/chorion membrane use in left-sided colectomy without a protective stoma: a multicenter pilot study.Frontiers in surgery · 2026Article
- Superior anal function in patients undergoing stoma closure within 6 months after LAR and analysis of factors associated with LARS syndrome: insights from experienced surgeons.Updates in surgery · 2025Review
- Machine learning-based prediction of permanent ileostomy in older adults after laparoscopic anterior resection for rectal cancer.Asia-Pacific journal of oncology nursing · 2025Article
- Extracellular Matrix Hydrogel Reduces Anastomotic Leaks in a Rodent Model of Rectal Anastomosis.The Journal of surgical research · 2025Article
- Prophylactic defunctioning stomas improve clinical outcomes of anastomotic leak following rectal cancer resections: An analysis of the US Rectal Cancer Consortium.International journal of colorectal disease · 2024Article
- Protective ileostomy after low anterior resection for extraperitoneal rectal cancer: does the reversal surgery timing affect closure failure?Updates in surgery · 2023Article
- Cost associated with diverting ostomy after rectal cancer surgery: a transnational analysis.Surgical endoscopy · 2023Article
- Article
- Comparative study between ghost ileostomy and defunctioning ileostomy in terms of morbidity and cost-effectiveness in low anterior resection for rectal cancer.Langenbeck's archives of surgery · 2021Article
- Assessment of the risk of permanent stoma after low anterior resection in rectal cancer patients.World journal of surgical oncology · 2020Article
- Long distance to hospital is not a risk factor for non-reversal of a defunctioning stoma.International journal of colorectal disease · 2019Article
- Loop-ileostomy reversal-patient-related characteristics influencing time to closure.International journal of colorectal disease · 2018Article
- Racial Disparities After Stoma Construction Exist in Time to Closure After 1 Year but Not in Overall Stoma Reversal Rates.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2018Article
- Hospital variation in sphincter preservation for elderly rectal cancer patients.The Journal of surgical research · 2014Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveFor low-lying rectal cancers, proximal diversion can reduce anastomotic leak after sphincter-preserving surgery; however, evidence suggests that such temporary diversions are often not reversed. We aimed to evaluate nonreversal and delayed stoma reversal in elderly patients undergoing low anterior resection (LAR).
designSEER-Medicare-linked analysis from 1991-2007. SETTINGS AND
participantsA total of 1179 primary stage I-III rectal cancer patients over age 66 who underwent LAR with synchronous diverting stoma.
main outcome measures(1) Stoma creation and reversal rates; (2) time to reversal; (3) characteristics associated with reversal and shorter time to reversal.
resultsWithin 18 mo of LAR, 51% of patients (603/1179) underwent stoma reversal. Stoma reversal was associated with age <80 y (P < 0.0001), male sex (P = 0.018), fewer comorbidities (P = 0.017), higher income (quartile 4 versus 1; P = 0.002), early tumor stage (1 versus 3; P < 0.001), neoadjuvant radiation (P < 0.0001), rectal tumor location (versus rectosigmoid; P = 0.001), more recent diagnosis (P = 0.021), and shorter length of stay on LAR admission (P = 0.021). Median time to reversal was 126 d (interquartile range: 79-249). Longer time to reversal was associated with older age (P = 0.031), presence of comorbidities (P = 0.014), more advanced tumor stage (P = 0.007), positive lymph nodes (P = 0.009), receipt of adjuvant radiation therapy (P = 0.008), more recent diagnosis (P = 0.004), and longer length of stay on LAR admission (P < 0.0001).
conclusionsHalf of elderly rectal cancer patients who undergo LAR with temporary stoma have not undergone stoma reversal by 18 mo. Identifiable risk factors predict both nonreversal and longer time to reversal. These results help inform preoperative discussions and promote realistic expectations for elderly rectal cancer patients.
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