Evidence map›Paper›PMID 23297786›Full record

ReviewAnnual review of clinical psychology2013

Cognitive interventions targeting brain plasticity in the prodromal and early phases of schizophrenia.

Melissa Fisher, Rachel Loewy, Kate Hardy, Danielle Schlosser, Sophia Vinogradov

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Annual review of clinical psychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02459210 nacompletednot on this mapstarted 2015, after this paper: background citation

CLUES (Cognition for Learning and for Understanding Everyday Social Situations): An Adaptation of Cognitive Enhancement Therapy for Persons at Clinical High Risk for Psychosis

TypeinterventionalSponsorBeth Israel Deaconess Medical CenterRan2015 to 2019Enrolled58ConditionsPsychosisArmsCLUES, therapy and computer games
NCT02817672 nawithdrawnnot on this mapstarted 2016, after this paper: background citation

Scaling a Smarter and More Efficient Intervention: Evaluating the Feasibility of Disseminating a Novel Mobile App Platform to Treat Depression

TypeinterventionalSponsorUniversity of California, San FranciscoRan2016 to 2018Enrolled0ConditionsDepressionArmsPRIME 1.0, PRIME 2.0
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. European Psychiatric Association guidance on treatment of cognitive impairment in schizophrenia.European psychiatry : the journal of the Association of European Psychiatrists · 2022
    Review
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  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Melissa FisherDepartment of Psychiatry, University of California, San Francisco, San Francisco, California 94143, USA.
Rachel Loewy
Kate Hardy
Danielle Schlosser
Sophia Vinogradov
University of California, San Francisco · USSan Francisco VA Medical Center · US

Funding

Neuroscience-Guided Cognitive Remediation in Adolescents at Risk for PsychosisR01MH081051 · NIMH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI VINOGRADOV, SOPHIA · 2008 to 2012
$2.4M
Neurobiological Mechanisms Underlying the Symptoms and Course of SchizophreniaT32MH089920 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FORD, JUDITH M · 2010 to 2014
$1.3M
NIMH NIH HHS R01 MH081051NIMH NIH HHS T32 MH089920
6 · The paper itself

Abstract

Several important paradigm shifts have occurred in the field of schizophrenia treatment, including an increased focus on early detection, the development of preemptive interventions, and the view of schizophrenia as a neurodevelopmental disease characterized by decreased efficiency and abnormal connectivity in cortical and subcortical neural networks. In this review, we briefly describe some of the neural impairments that contribute to the development of schizophrenia, with an emphasis on the impact of stress and trauma on cognitively vulnerable neural systems. We then present current data on two behavioral interventions that target these critical risk factors and that aim to preempt the onset of schizophrenia in vulnerable individuals or improve the clinical course in recent-onset schizophrenia: cognitive therapy and computerized cognitive training.

Indexed as

Prodromal SymptomsSchizophrenic PsychologyCognitive Behavioral TherapyHumansNeuronal PlasticitySchizophrenia

Identifiers

PMID23297786
PMCPMC4745413
OpenAlexW2165398545

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.