Evidence map›Paper›PMID 23297719›Full record

GuidelineHPB : the official journal of the International Hepato Pancreato Biliary Association2013

Selection for hepatic resection of colorectal liver metastases: expert consensus statement.

Reid B Adams, Thomas A Aloia, Evelyne Loyer, Timothy M Pawlik, Bachir Taouli, Jean-Nicolas Vauthey, Americas Hepato-Pancreato-Biliary Association, Society of Surgical Oncology, Society for Surgery of the Alimentary Tract

Open access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 8 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 8 syntheses or guidelines pooled it, 343 citations in OpenAlex.

  1. Missing colorectal liver metastases: the surgical challenge.Langenbeck's archives of surgery · 2021
    Pooled it
  2. Pooled it
  3. Mini-invasiveWorld journal of gastroenterology · 2019
    Pooled it
  4. Pooled it
  5. Pooled it
  6. A systematic review of repeat hepatectomy for recurrent colorectal liver metastases.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013
    Pooled it
  7. Selection for hepatic resection: expert consensus conference.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2013
    Guideline
  8. BRAZILIAN CONSENSUS FOR MULTIMODAL TREATMENT OF COLORECTAL LIVER METASTASES. MODULE 3: CONTROVERSIES AND UNRESECTABLE METASTASES.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery
    Guideline
  9. Trial
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  12. Article
  13. Review
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  18. Free-breathing phase-sensitive inversion recovery TMagnetic resonance in medicine · 2026
    Article
  19. Article
  20. Review

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Reid B AdamsDivision of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA.
Thomas A Aloia
Evelyne Loyer
Timothy M Pawlik
Bachir Taouli
Jean-Nicolas Vauthey
Americas Hepato-Pancreato-Biliary Association
Society of Surgical Oncology
Society for Surgery of the Alimentary Tract
The University of Texas MD Anderson Cancer Center · USJohns Hopkins University · USMount Sinai Hospital · USUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic resection offers a chance of a cure in selected patients with colorectal liver metastases (CLM). To achieve adequate patient selection and curative surgery, (i) precise assessment of the extent of disease, (ii) sensitive criteria for chemotherapy effect, (iii) adequate decision making in surgical indication and (iv) an optimal surgical approach for pre-treated tumours are required. For assessment of the extent of the disease, contrast-enhanced computed tomography (CT) and/or magnetic resonance imaging (MRI) with gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) is recommended depending on the local expertise and availability. Positron emission tomography (PET) and PET/CT may offer additive information in detecting extrahepatic disease. The RECIST criteria are a reasonable method to evaluate the effect of chemotherapy. However, they are imperfect in predicting a pathological response in the era of modern systemic therapy with biological agents. The assessment of radiographical morphological changes is a better surrogate of the pathological response and survival especially in the patients treated with bevacizumab. Resectability of CLM is dependent on both anatomic and oncological factors. To decrease the surgical risk, a sufficient volume of liver remnant with adequate blood perfusion and biliary drainage is required according to the degree of histopathological injury of the underlying liver. Portal vein embolization is sometimes required to decrease the surgical risk in a patient with small future liver remnant volume. As a complete radiological response does not signify a complete pathological response, liver resection should include all the site of a tumour detected prior to systemic treatment.

Indexed as

HepatectomyPatient SelectionAngiogenesis InhibitorsAntibodies, Monoclonal, HumanizedBevacizumabColorectal NeoplasmsConsensus Statements as TopicContrast MediaGadoliniumHumansLiver NeoplasmsMagnetic Resonance ImagingMultimodal ImagingNeoplasm StagingPositron-Emission TomographyRisk AssessmentAngiogenesis InhibitorsAntibodies, Monoclonal, HumanizedBevacizumabContrast MediaGadolinium

Identifiers

PMID23297719
PMCPMC3719914
OpenAlexW2025639003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.