ArticleProceedings of the National Academy of Sciences of the United States of America2013
Genomic basis for coral resilience to climate change.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 285 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
285 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Limited plasticity in thermally tolerant ectotherm populations: evidence for a trade-off.Proceedings. Biological sciences · 2021Pooled it
- Twenty-Five Years of the Environmental Stress Response and the Enduring Power of Yeast in Stress Biology.Yeast (Chichester, England) · 2026Review
- Algae-specific immune modulation influences responses to heat and pathogen challenge in a symbiotic coral.Science advances · 2026Article
- Heat-evolved coral photosymbionts exhibit dampened stress responses across distinct physiological contexts.The New phytologist · 2026Article
- With a Little Help From Their Friends: Endolithic Microbial Communities Modulate Mussel Survival, Behaviour and Molecular Responses Under Thermal Stress.Molecular ecology · 2026Article
- Neighboring Gulf Killifish (Ecology and evolution · 2026Article
- Article
- A new era for coral functional genomics.Nature protocols · 2026Article
- Microgeographic differentiation in the genetic structure of catch bowl coral, Isopora cf. palifera (Scleractinia; Acroporidae), in Kenting National Park, Taiwan.Scientific reports · 2026Article
- Transcriptional responses of reef-building coral Leptoria phrygia to localized thermal anomalies: a seasonal and experimental approach.Scientific reports · 2026Article
- Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Mild Warming Induces Divergent Plastic Responses in Gene Expression Among Populations of a Temperate Butterfly.Molecular ecology · 2026Article
- A Cross-Climate Comparison of Molecular Phenology in Three Tropical and Temperate Trees.Plant-environment interactions (Hoboken, N.J.) · 2026Article
- NF-κB: A Diverse and Multifunctional Transcription Factor in Holozoans.Molecular biology and evolution · 2026Review
- Heat exposure improves acute copper tolerance in the intertidal copepod Tigriopus californicus.Environmental science and pollution research international · 2026Article
- Metaproteome Analysis of Short-Term Thermal Stress in Three Sympatric Coral Species Reveals Divergent Host Responses.Ecology and evolution · 2026Article
- Differential Responses to Heat Stress Between Freshly Isolated and Long-Term CulturedMicroorganisms · 2026Article
- Drought-associated genes exhibit high constitutive expression in Quercus douglasii, a drought-tolerant California oak.G3 (Bethesda, Md.) · 2026Article
- Evidence of a genomic basis for growth rate variation in a natural kelp population.Scientific reports · 2026Article
- Acute Heat Priming Dampens Gene Expression Response to Thermal Stress in a WidespreadEcology and evolution · 2026Article
225 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent advances in DNA-sequencing technologies now allow for in-depth characterization of the genomic stress responses of many organisms beyond model taxa. They are especially appropriate for organisms such as reef-building corals, for which dramatic declines in abundance are expected to worsen as anthropogenic climate change intensifies. Different corals differ substantially in physiological resilience to environmental stress, but the molecular mechanisms behind enhanced coral resilience remain unclear. Here, we compare transcriptome-wide gene expression (via RNA-Seq using Illumina sequencing) among conspecific thermally sensitive and thermally resilient corals to identify the molecular pathways contributing to coral resilience. Under simulated bleaching stress, sensitive and resilient corals change expression of hundreds of genes, but the resilient corals had higher expression under control conditions across 60 of these genes. These "frontloaded" transcripts were less up-regulated in resilient corals during heat stress and included thermal tolerance genes such as heat shock proteins and antioxidant enzymes, as well as a broad array of genes involved in apoptosis regulation, tumor suppression, innate immune response, and cell adhesion. We propose that constitutive frontloading enables an individual to maintain physiological resilience during frequently encountered environmental stress, an idea that has strong parallels in model systems such as yeast. Our study provides broad insight into the fundamental cellular processes responsible for enhanced stress tolerances that may enable some organisms to better persist into the future in an era of global climate change.
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