Evidence map›Paper›PMID 23296213›Full record

Trial reportObesity facts2012

Contingency management for the treatment of antipsychotic-induced weight gain: a randomized controlled pilot study.

Joseph C Ratliff, Laura B Palmese, K Melek Tonizzo, Lydia Chwastiak, Cenk Tek

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Obesity facts, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 6 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 6 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Joseph C RatliffDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA. Jose516@hotmail.com
Laura B Palmese
K Melek Tonizzo
Lydia Chwastiak
Cenk Tek
Yale University · US

Funding

Lifestyle Modification to Reduce Weight and Related Morbidity in Mental IllnessR01MH080048 · NIMH · YALE UNIVERSITY · PI TEK, CENK · 2009 to 2010
$1.3M
NIMH NIH HHS R01 MH080048NIMH NIH HHS R01 MH080048-02
6 · The paper itself

Abstract

objectiveWeight gain is common for individuals with serious mental illness (SMI) receiving antipsychotic drug therapy. Contingency management (CM) is a behavioral intervention that rewards positive performance and has demonstrated effectiveness in reducing drug use in SMI populations. This study evaluated the feasibility of using CM to promote weight loss in individuals with SMI over 8 weeks.

method30 individuals (BMI ≥ 28 kg/m(2)) were randomized to one of three conditions: i) The combination of a standardized lifestyle modification (LM) program for individuals with SMI and payment for group attendance (CM(attendance)), ii) The combination of LM and payment for weight loss (CM(weight)), and iii) waitlist control (CON). After the waitlist period, those participants joined a LM group and received payment for behavioral change (CM(behavior)).

resultsSubjects in the CM(attendance) and in the CM(weight) group lost a mean of 1.16 kg and 1.23 kg, respectively, while subjects in the CON gained a mean of 0.68 kg. Subjects receiving CM(behavior), lost a mean of 2.54 kg, which was a significant weight loss compared to the control period.

conclusionLM supplemented with CM may facilitate weight loss in patients taking antipsychotic medications; financial reimbursement for behavioral change may be particularly effective in this population.

Indexed as

Health BehaviorLife StyleWeight GainWeight LossAdultAntipsychotic AgentsBehavior TherapyBody Mass IndexFemaleHumansMaleMental DisordersMiddle AgedObesityPatient CompliancePilot ProjectsAntipsychotic Agents

Identifiers

PMID23296213
PMCPMC6902254
OpenAlexW1973188185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.