ArticleJournal of biomedical optics2013
Two-step reconstruction method using global optimization and conjugate gradient for ultrasound-guided diffuse optical tomography.
Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
3-D Simultaneous Ultrasound and NIR Imaging for Breast Cancer Detection
Optical Monitoring of Neoadjuvant Chemotherapy and Prediction of Pathological Complete Response in Breast Cancer Patients
Who cites it
9 citing papers in PubMed.
- DOT-AE-GAN: a hybrid autoencoder-GAN model for enhanced ultrasound-guided diffuse optical tomography reconstruction.Journal of biomedical optics · 2025Article
- Automated pipeline for breast cancer diagnosis using US assisted diffuse optical tomography.Biomedical optics express · 2023Article
- Machine learning model with physical constraints for diffuse optical tomography.Biomedical optics express · 2021Article
- Reducing image artifact in diffuse optical tomography by iterative perturbation correction based on multiwavelength measurements.Journal of biomedical optics · 2019Article
- Improving DOT reconstruction with a Born iterative method and US-guided sparse regularization.Biomedical optics express · 2019Article
- Two step imaging reconstruction using truncated pseudoinverse as a preliminary estimate in ultrasound guided diffuse optical tomography.Biomedical optics express · 2017Article
- Dimensionality Reduction Based Optimization Algorithm for Sparse 3-D Image Reconstruction in Diffuse Optical Tomography.Scientific reports · 2016Article
- Estimation and imaging of breast lesions using a two-layer tissue structure by ultrasound-guided optical tomography.Journal of biomedical optics · 2015Article
- Diffuse reflectance optical topography: location of inclusions in 3D and detectability limits.Biomedical optics express · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Ultrasound-guided diffuse optical tomography (DOT) is a promising method for characterizing malignant and benign lesions in the female breast. We introduce a new two-step algorithm for DOT inversion in which the optical parameters are estimated with the global optimization method, genetic algorithm. The estimation result is applied as an initial guess to the conjugate gradient (CG) optimization method to obtain the absorption and scattering distributions simultaneously. Simulations and phantom experiments have shown that the maximum absorption and reduced scattering coefficients are reconstructed with less than 10% and 25% errors, respectively. This is in contrast with the CG method alone, which generates about 20% error for the absorption coefficient and does not accurately recover the scattering distribution. A new measure of scattering contrast has been introduced to characterize benign and malignant breast lesions. The results of 16 clinical cases reconstructed with the two-step method demonstrates that, on average, the absorption coefficient and scattering contrast of malignant lesions are about 1.8 and 3.32 times higher than the benign cases, respectively.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.